CasNo.144701-48-4,High Quality Raw Material Telmisartan CAS 144701-48-4 for Hypertension Treatment,(144701-48-4) Suppliers

1 Kilogram	FOB Price: USD 60.0000

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T,

Keywords

Telmisartan Telmisartan powder 144701-48-4

Quick Details

Appearance:White powder
Application:The raw material for medicine
PackAge:1kg/bag; 25kg/drum, or as customer's request.
ProductionCapacity:500|Metric Ton|Quarter
Storage:Store in cool & dry place. Store in well-closed containers.
Transportation:By express,by air,by sea,door to door.

Superiority:

Rich experience.

We have specialized in this field for 7 years. our steroids and hormones have been exported to overseas, like europe, africa, asia, america and other countries. and we have got very good feedback from our customers, and established long friendly relations of cooperation.

High quality products with the best price

1.All powders are factory directly supplying and have much in stock.

2.Before each powder send out, it all will be tested again by our technician, if the quality good, then it can be sent out to customers.

Professtional packing and fast delivery

1.Professtional team for packing, different country and quantity order have different packing way, sure package the products the best to your order.

2.We have mass stock, so that we can guarantee all the package can be sent out as soon as possible after you pay and should arrive your hands 3-7 days safely by dhl,tnt,fedex,hkems,ups,etc.

Best pre-sell and after-sell service.

1.Once the package send out, tracking number and packing picture should email you later

2.For raw powder buyer, we also can help you cook steroid powder into injection and supply you all the things to make ready use injection, such as 10ml vials,0.22um-0.45um whatman filter,crimper machine and filter pump.

Details:

High Quality Raw Material Telmisartan CAS 144701-48-4 for Hypertension Treatment

Product Name	Telmisartan
Specification	Pure
Lead time	Usually about 8-12 days
Shipment	DHL, FedEx, EMS, TNT, By Air or By sea if large quantity
Payment	Alibaba Trade Assurance, , TT, Accept Euros
Package	1kg by cartons, 25kg by drums, or as customers' request
Quality	Guaranteed, Support refund fully if poor quality
NOTE	The info on web just for reference showing, Pls contact Marshall and ask for more details, including price & COA and so on.

Telmisartan, chemically named 4 '-[4-methyl-6 -(1-methyl-1h-benzimidazol-2-yl) -2-propyl - 1h-benzimidazol-1-yl] biphenyl - 2-carboxylic acid, molecular formula is C33H30N4O2, white or white crystalline powder, odorless, tasteless. Soluble in trichloromethane, slightly soluble in dichloromethane or dimethylformamide, slightly soluble in methanol, very slightly soluble in ethanol, almost insoluble in water, soluble in 1mol/L sodium hydroxide solution, very slightly soluble in 0.1mol/L hydrochloric acid solution.

Function:

Non-peptide angiotensin ⅱ receptor antagonists selectively and irreversibly block ATI receptors without affecting other receptor systems. For mild to moderate hypertension. Telmisartan, a novel antihypertensive drug, is a specific angiotensin ⅱ receptor antagonist (AT ⅰ type) and is used in the treatment of essential hypertension. The replacement angiotensin ⅱ receptor binds with high affinity to the AT ⅰ receptor subtype (known angiotensin ⅱ action site). Telmisartan has no site agonist effect on AT ⅰ receptor site, and selectively binds to AT ⅰ receptor for a long time. There is no affinity for other receptors, including AT2 and other LESS characteristic AT receptors. The function of these other receptors is unknown, as is the possible overstimulation effect of telmisartan on angiotensin II levels. Telmisartan did not inhibit renin in human plasma or block ion channels. It did not inhibit angiotensin converting enzyme ⅱ, which could also degrade the adverse reactions caused by bradykinin enhancement. The elevated blood pressure induced by angiotensin ⅱ was almost completely inhibited by telmisartan 80mg in human. The inhibitory effect lasted 24 hours and could still be detected at 48 hours. The antihypertensive effect was gradually obvious within 3 hours after the first dose. Maximum hypotensive effects are achieved 4 weeks after the start of treatment and can be maintained over the long term. If treatment is abruptly interrupted, blood pressure gradually returns to pre-treatment levels after several days without rebound hypertension. In clinical trials that directly compared the two hypertension drugs, the incidence of dry cough was significantly lower in patients treated with angiotensin-converting enzyme inhibitors.