CasNo.274901-16-5,Best Quality Vildagliptin CAS 274901-16-5 for Antidiabetic,(274901-16-5) Suppliers

1 Kilogram	FOB Price: USD 480.0000

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T,

Keywords

Vildagliptin Vildagliptin Powder 274901-16-5

Quick Details

Appearance:White powder
Application:The raw material for medicine
PackAge:1kg/bag; 25kg/drum, or as customer's request.
ProductionCapacity:500|Metric Ton|Quarter
Storage:Store in cool & dry place. Store in well-closed containers.
Transportation:By express,by air,by sea,door to door.

Superiority:

Rich experience.

We have specialized in this field for 7 years. our steroids and hormones have been exported to overseas, like europe, africa, asia, america and other countries. and we have got very good feedback from our customers, and established long friendly relations of cooperation.

High quality products with the best price

1.All powders are factory directly supplying and have much in stock.

2.Before each powder send out, it all will be tested again by our technician, if the quality good, then it can be sent out to customers.

Professtional packing and fast delivery

1.Professtional team for packing, different country and quantity order have different packing way, sure package the products the best to your order.

2.We have mass stock, so that we can guarantee all the package can be sent out as soon as possible after you pay and should arrive your hands 3-7 days safely by dhl,tnt,fedex,hkems,ups,etc.

Best pre-sell and after-sell service.

1.Once the package send out, tracking number and packing picture should email you later

2.For raw powder buyer, we also can help you cook steroid powder into injection and supply you all the things to make ready use injection, such as 10ml vials,0.22um-0.45um whatman filter,crimper machine and filter pump.

Details:

Best Quality Vildagliptin CAS 274901-16-5 for Antidiabetic

Product Name	Vildagliptin
Specification	Pure
Lead time	Usually about 8-12 days
Shipment	DHL, FedEx, EMS, TNT, By Air or By sea if large quantity
Payment	Alibaba Trade Assurance, , TT, Accept Euros
Package	1kg by cartons, 25kg by drums, or as customers' request
Quality	Guaranteed, Support refund fully if poor quality
NOTE	The info on web just for reference showing, Pls contact Marshall and ask for more details, including price & COA and so on.

Vildagliptin (LAF-237; NVP-LAF 237) inhibits DPP-4 with IC50 of 2.3 nM.IC50 Value: 2.3 nM.Target: DPP-4in vitro: Vildagliptin is an N-substituted glycyl-2-cyanopyrrolidine (figure 2). It is a potent competitive and reversible inhibitor of human and rodent DPP-4 in vitro, with a median inhibitory concentration (IC50) ~2-3 nmol/L. Importantly, vildagliptin inhibits DPP-4 with high specificity relative to other similar peptidases where its IC50 exceeds 200 mol/L.in vivo: Compared to age-, gender-, BMI-matched subjects with normal renal function, the mean AUC of vildagliptin after 14 days in patients with mild, moderate, and severe RI increased by 40%, 71%, and 100%, respectively. The treatment was effective in modulating stress in pancreatic tissue, both by reducing levels of stress markers as well as by increasing activity of SOD and catalase. After analyzing the pancreatic histology, we found that vildagliptin was also able to preserve islets and pancreatic β-cells, especially at the concentration of 5 mg/kg.