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Sulfamethoxazole Sinomine Trimethoprim
Neoamine alias sulfamethoxazole, chemical name N-(5-methyl-3-isooxazolyl) -4-aminobenzene sulfonamide, molecular formula is C10H11N3O3S, molecular weight is 253.28. Is a broad - spectrum antibiotic, belongs to the first class antibacterial. White crystalline powder, odorless, slightly bitter taste; Almost insoluble in water, soluble in dilute hydrochloric acid, sodium hydroxide solution or ammonia solution. Used as sulfa antibacterial and anti-inflammatory drugs for urinary tract infection, respiratory tract infection, suppurative skin infection, tonsillitis.
What is function of Sulfamethoxazolel
Lufenuron is mainly used for prevention and treatment of cotton, corn, vegetables, fruit trees and otherLepidoptera larvae; also serve as health agents; can be used to control pest animals such as cattle.
The main indications are the following infections caused by sensitive strains:
1. Urinary tract infections caused by sensitive strains of Escherichia coli, Klebsiella, Enterobacter, Proteus mirae, Proteus common and Morganella.
2. Acute otitis media in children over 2 years of age caused by Streptococcus pneumoniae or Haemophilus influenzae.
3. Acute attack of chronic bronchitis in adults caused by Streptococcus pneumoniae or Haemophilus influenzae.
4. Intestinal infection and shigella infection caused by shigella fowleri or Song Shigella sensitive strains.
5. This strain is preferred for the treatment of pneumocystis carinii pneumonia.
Usage:
Sulfanilamide antibacterial anti-inflammatory drugs, used for urinary tract infection, respiratory tract infection, suppurative skin infection, tonsillitis; It is contraindicated to patients allergic to sulfa and patients with severe liver and kidney diseases. The antibacterial spectrum was similar to SD, but the antibacterial effect was stronger. The solubility of acetyl, the metabolite of sulfonamide drugs in the body, is low, and it is easy to crystallize in the urethra and cause crystalline urine, hematuria and closed urine, etc., and sodium bicarbonate should be taken together with large doses of sulfonamide drugs. When combined with TMP, its antibacterial efficacy was significantly enhanced, which could be increased by several times to tens of times. Clinical use for tonsillitis, acute bronchitis, lung infection, urinary tract infection, skin suppurative infection, dysentery and typhoid, etc.
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