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Fosfomycin Fosfomycin calcium fosfomycin sodium
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English name Fosfomycin
Chemical formula C3H7O4P
Molecular weight 138.06
CAS accession number 23155-02-4
EINECS Accession No. 245-463-1
Density 1.561 g/cm³
Melting point 94 ℃
Boiling point 342.65 ℃
Flash point 161.03 ℃
Water-soluble and easily soluble
Refractive index 1.486
Fosfomycin, whose chemical name is (1R,2S)-1,2-epoxycis propylene phosphate, and whose molecular formula is C3H7O4P, is an antibiotic. Originally isolated from Streptomyces fradicle, it is effective against Gram-positive and negative bacteria. Its mechanism of action is to inhibit the synthesis of bacterial cell walls. It can be combined with a bacterial cell wall synthase to hinder the first reaction of bacteria to use related substances to synthesize cell wall, thereby playing a bactericidal effect. Mainly used for urinary tract, skin and soft tissue, intestinal infections caused by sensitive Gram-negative bacteria
pharmacological action
This product has a wide antibacterial spectrum, and has high antibacterial activity against Staphylococcus, Escherichia coli, Serratia and Shigella, etc., against Pseudomonas aeruginosa, Proteus, Aerogenes, Pneumococcus, Streptococcus and some Anaerobic bacteria also have a certain antibacterial effect, but they are worse than penicillins and cephalosporins. Bacteria have no cross-resistance between this product and other antibiotics.
[Storage] Stored in a clean, cool and dry area; keep away from strong, direct light.
[Shelf Life] 2 years when properly stored.
[Packing]
Inner double plastic bags--25kg/Fiber drum (35*35*53cm, GW: 28kg, NW: 25kg, 0.06CBM);
Inner double plastic bags--5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg);
Inner double plastic bags--1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
[Delivery] 5 working days after payment.
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