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100 Gram |
FOB Price: USD 300.0000 |
Tianeptine sodium 30123-17-2 High purity API powder
Wuhan Senwayer century chemical Co..Ltd located in the predominant Wuhan City where is a traffic hinge of China, specialize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.
We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and other places.
Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.
We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.
CAS:30123-17-2
Molecular formula: C21H24ClN2NaO4S
Molecular weight:458.93
EINECS NO.:250-059-3
Melting Point: 1800°C
Tianaputin sodium is a tricyclic antidepressant, and its antidepressant mechanism is different from that of traditional tricyclic antidepressants. It can increase the reuptake of 5-ht in the synaptic space, and may improve the effect of 5-ht neuron conduction. No affinity for choline. The antidepressant effect was similar to that of tricyclic group, but the tolerance was better than that of tricyclic group. In animal experiments, it can increase the spontaneous activity of pyramidal cells in the hippocampus and accelerate the recovery of inhibited functions. It increases the reabsorption of serotonin by neurons in the cerebral cortex and hippocampus. Thianaputin sodium is absorbed rapidly and completely in the digestive tract. Distribution is rapid, with PPB as high as 94%. In the liver by -oxidation and n-demethylation metabolism complete clearance terminal t1/2 short, 2.5 h, very little protodrug (8%) excreted from the kidney, mainly its metabolites excreted from the urine. In patients with renal insufficiency, clearance of t1/2 was prolonged for 1h.
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