Dexamethasone Base

Superiority:

Product Name:    Dexamethasone
Synonyms:    DEXAMETHASONE BASE;DEXAMETHASONUM;DEXAMETHASON;DEXAMETHASONE;CALONAT;(11BETA,16ALPHA)-9-FLUORO-11,17,21-TRIHYDROXY-16-METHYLPREGNA-1,4-DIENE-3,20-DIONE;(11B,16A)-9-FLUORO-11,17,21-TRIHYDROXY-16-METHYL-PREGNA-1,4-DIENE-3,20-DIONE;1,4-PREGNADIEN-9ALPHA-FLUORO-16ALPHA-METHYL-11BETA, 17ALPHA, 21-TRIOL 3,20-DIONE
CAS:    50-02-2
MF:    C22H29FO5
MW:    392.47
EINECS:    200-003-9
Product Categories:    Active Pharmaceutical Ingredients;Antitumors for Research and Experimental Use;Biochemistry;Hydroxyketosteroids;Steroids;Isotope Labeled Compounds;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;Pharmaceutical intermediate;API;Mainly used for anti-inflammatory and allergy;Pharmaceutical intermediates;pharmaceutical intermediate and medicine grade;MAXIDEX;Hormone Drugs
Mol File:    50-02-2.mol
Dexamethasone Structure
Dexamethasone Chemical Properties
Melting point     262-264 °C (lit.)
alpha     75 º (c=1, dioxane)
Boiling point     568.2±50.0 °C(Predicted)
density     1.1283 (estimate)
refractive index     76 ° (C=1, Dioxane)
Fp     9℃
storage temp.     2-8°C
solubility     ethanol: 1 mg/mL
form     powder
pka    12.13±0.70(Predicted)
color     off-white
Water Solubility     10 mg/100 mL (25 ºC)
Sensitive     Light Sensitive
Merck     14,2943
BRN     2066651
Stability:    Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.
InChIKey    UREBDLICKHMUKA-CXSFZGCWSA-N
CAS DataBase Reference    50-02-2(CAS DataBase Reference)
NIST Chemistry Reference    Prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2)
EPA Substance Registry System    Dexamethasone (50-02-2)
Safety Information
Hazard Codes     Xi,Xn,T,F
Risk Statements     43-40-36/37/38-20/21/22-42/43-39/23/24/25-23/24/25-11
Safety Statements     36/37-45-36-26-22-16
RIDADR     UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany     2
RTECS     TU3980000
TSCA     Yes
HS Code     29372210
Hazardous Substances Data    50-02-2(Hazardous Substances Data)
Toxicity    LD50 oral in rat: > 3gm/kg