CasNo.54-35-3,Procaine penicillin G CAS NO.54-35-3,(54-35-3) Suppliers

1 Kilogram	FOB Price: USD 5.0000

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Procaine penicillin G BENZYLPENICILLIN PROCAIN SALT (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenylethyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Quick Details

Appearance:colourless viscous liquid
Application:Synthetic fragrances
PackAge:drum
ProductionCapacity:10000|Metric Ton|Month
Storage:Room temperature
Transportation:By Sea/Air/DHL

Superiority:

We are leading fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:

1.Noble Metal Catalysts (Pt.Pd...)

2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)

3.OLED intermediates (Fluorene,Carbazole,Boric acid...)

4.Customs Synthesis

Our advantage:

1.Higest quality and good package

2.Fast delivery

3.Better payment term

4.Fast response to customer within 6 hours

5.Good business credit in Europe ,US ,Japan ,Korea

Anyway ,if you need any chemicals from China ,Henan Wentao can help you

Details:

Procaine penicillin G Basic information

Product Name:	Procaine penicillin G
Synonyms:	BENZYLPENICILLIN PROCAIN SALT;PROCAINE BENZYLPENICILLIN;PROCAINE PENICILLIN G;PENICILLIN G PROCAINE;PENICILLIN-G PROCAIN SALT;Procaine penicillin G(1% lecithin/citrate acid);Penicillin G procaine +1% lecithin CP200/BP/USP/EP;Procain Penicillin G
CAS:	54-35-3
MF:	C29H38N4O6S
MW:	570.7
EINECS:	200-205-7
Product Categories:	PHARMACEUTICALS
Mol File:	54-35-3.mol

Procaine penicillin G Chemical Properties

Melting point	129-130 °C
density	1.1335 (rough estimate)
refractive index	1.6000 (estimate)
CAS DataBase Reference	54-35-3
EPA Substance Registry System	4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1) (54-35-3)

Safety Information

Toxicity

LD50 orl-rat: >2 g/kg ABANAE 3,534,55/56

MSDS Information

Procaine penicillin G Usage And Synthesis

Chemical Properties	White, fine crystals or powder; odorless; relatively stable to air and light; solutions dextroro- tatory. Sparingly soluble in water; slightly soluble in alcohol; fairly soluble in chloroform.
Originator	Duracillin,Lilly,US,1948
Uses	Antibacterial.
Manufacturing Process	There was added to 250 ml of a concentrated butyl acetate extract containing 74,000 units of the acid form of penicillin per ml, 50 ml of a butyl acetate solution containing 0.238 g per ml of procaine base. The solution was agitated for one hour. The precipitate which formed was very gummy and not in the form of discrete crystals. This precipitate was crystallized by scratching the side of the vessel and agitating further. After this treatment 18.25 g of crystalline procaine penicillin was obtained which assayed 1010 units per mg representing a yield of 99.6% of the activity contained in the concentrated extract.
Brand name	Duracillin(Lilly); Pfizerpen (Pfizer).
Therapeutic Function	Antibacterial
General Description	The first widely used amine salt of penicillin G wasmade with procaine. Penicillin G procaine (Crysticillin,Duracillin, Wycillin) can be made readily from penicillin Gsodium by treatment with procaine hydrochloride. This saltis considerably less soluble in water than the alkali metalsalts, requiring about 250 mL to dissolve 1 g. Free penicillinis released only as the compound dissolves and dissociates.It has an activity of 1,009 units/mg. A large number ofpreparations for injection of penicillin G procaine are commerciallyavailable. Most of these are either suspensions inwater to which a suitable dispersing or suspending agent, a buffer, and a preservative have been added or suspensions inpeanut oil or sesame oil that have been gelled by theaddition of 2% aluminum monostearate. Some commercialproducts are mixtures of penicillin G potassium or sodiumwith penicillin G procaine; the water-soluble salt providesrapid development of a high plasma concentration of penicillin,and the insoluble salt prolongs the duration of effect.
Safety Profile	Moderately toxic by intraperitoneal and intramuscular routes. Slightly toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic vapors of NOx, and SOx.