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4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE Tofacitinib Impurity R 4-Chloro-7-tosyl-7H-pyrrolo[2
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4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE Basic information |
Product Name: | 4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE |
Synonyms: | Tofacitinib Impurity R;4-Chloro-7-(p-tolylsulfonyl)pyrrolo[2,3-d]pyrimidine;4-CHLORO-7-[(4-METHYLPHENYL)SULFONYL]-7H-PYRROLO[2,3-D]PYRIMIDINE;4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE;4-Chloro-7-tosyl-7H-pyrro...;4-Chloro-7-[(4-methylbenzene)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine;4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine;7H-Pyrrolo[2,3-D]pyriMidine,4-chloro-7-[(4-Methylphenyl)sulfonyl]- |
CAS: | 479633-63-1 |
MF: | C13H10ClN3O2S |
MW: | 307.76 |
EINECS: | 811-000-2 |
Product Categories: | Heterocycle-Pyrimidine series |
Mol File: | 479633-63-1.mol |
4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE Chemical Properties |
Melting point | 145.0 to 149.0 °C |
Boiling point | 505.3±60.0 °C(Predicted) |
density | 1.49 |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
pka | 1.73±0.30(Predicted) |
InChIKey | BTOJSYRZQZOMOK-UHFFFAOYSA-N |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 22 |
HazardClass | IRRITANT |
MSDS Information |
4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE Usage And Synthesis |
Uses | 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine is a reagent in the synthesis of (+)-tofacitinib, a selective Janus kinase 3 inhibitor (JAK3) and an immunosuppressant drug. |
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