Veterinary Medicine Antiparasitic Drug Ivermectin CAS: 70288-86-7

Details:

The Introductction of Ivermectin:

Ivermectin is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod,
canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum resistant parasites.
Ivermectin for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae
effectively, but for adult worms; For only in intestinal fecal round worms are also effective.
Ivermectin has the selective inhibitory effect, with no spinal nerve cells and muscle cells in the animal glutamic acid ion channels of the valve is the high binding affinity, leading to the proliferation of the chloride ion permeability of cell membrane, cause nerve cells or muscle cells hyperpolarization, parasites paralysis or death.

The Application & Function of Ivermectin:

1. Ivermectin is the derivatives of abamectin. Ivermectin belongs to semisynthetic broad-spectrum resistant parasites.
2. Ivermectin has effect for most of the various life cycle nematodes.
3. Ivermectin has effect for the microfilaria of onchocerca volvulus,but it does not has effect for the adult onchocerca volvulus.
4. Ivermectin has effect for dung round worms that is only stay in intestinal tract.
5. Ivermectin has selective inhibition.
6. Ivermectin can not go through the blood brain barrier of humanbeings.