High Quality Pramipexole 191217-81-9 Powder With Best Price

Details:

Company description:

Wuhan Godbullraw Chemical Co.,ltd, founded in 2011, is a modern advanced enterprise specializing in custom synthesis and R&D and exportation of APIs, peptides, Sarms, Local anesthetics, plant extract etc, we build coopration with labs and factory qualitied with GMP, DMF, FDA in china and worldwild. We take advantage on integrating factory resources and lab customized projects.for customer demand, we continue to expand the industry chain in familiar areas, and at the same time we also keep develop new product supply chain.

We have 7 synthesis labs and 3 scale-up  labs and 3 analysis lab toatly spaced with 13500 square meters, basement of these experienced chemist with high educated, we have strong supply system and purity raw. As the shipping , we cooperate with 10 experienced shipping companies to make sure ETA by a safe delivery to worldwild.

 

Usage:Pramipexole powder is A dopamine-D2-receptor agonist. Antiparkinsonian

1. Pramipexole is a dopamine agonist belonging to the same class of drugs as Cabergoline. The primary purpose of this drug is in the treatment of Parkinson's disease.

 

2. Pramipexole is most commonly found under the brand names Sifrol, Mirapexin and Mirapex, although generics are also available. Mirapex is the most well known brand by Boehringer Ingelheim Pharmaceuticals.

 

3. Along with treating Parkinson's, Pramipexole is also prescribed for the treatment of restless legs syndrome. The drug has also shown promising signs in the treatment of bipolar depression, although it has never officially held this label.

4. Pramipexole is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) and restless legs syndrome (RLS).It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants.

 

5. Pramipexole has shown robust effects on pilot studies in a placebo-controlled proof of concept study in bipolar disorder. It is also being investigated for the treatment of clinical depression and fibromyalgia.

Application:

1. Pramipexole is a dopamine agonist that directly correlates with the prolactin hormone. As dopamine levels in the body go up, prolactin levels go down. It does this by having a direct effect on the dopamine D3 receptor. Although it also acts on the D2 receptor its affinity for the D3 receptor is seven times greater than any existing dopamine agonist.

2. The effect of Pramipexole on the D3 receptor has a strong impact on the neurological system, which is why it's used to treat Parkinson's disease and in some cases Alzheimer's disease. Through acting on the D3 receptor, Pramipexole also affects a man's sexual interest and activity. 

3. Prolactin is in part directly responsible for a man's refractory period, which refers to the time it takes to recover from sexual activity so that performance can occur again. By lowering prolactin through an increase in dopamine, Pramipexole can directly reduce the refractory period resulting in the ability to perform sexually more frequently.

Usage:

1. To alleviate the symptoms of Parkinson's disease: Parkinson's disease is due to the movement of brain dopaminergic neuron loss caused by dopamine deficiency, lead to patients with tremor, rigidity and bradykinesia and a series of symptoms.

 

2. Hydrochloric acid highly selective effects on dopamine D2 and D3 receptor agonist, dopamine release, improve motor symptoms. Research on Shannon display, early Parkinson's disease patients pramipexole monotherapy after, can effectively control the motor symptoms in patients with early stage, to help maintain the ability of daily life.

 

3. Pramipexole in combination with levodopa can effectively improve the ADL score and motor symptoms in patients with advanced Parkinson's disease score in patients with advanced Parkinson's disease, make life more vibrant.

 

Our service:

Quality:  Our products match CP and USP standard before comes out from factory and rechecked by third institution like Jonashik and scores well always, we supply test report credit 30$ for next order

Shipping: available to worldwide, ETA 12 days around,customer just only need to supply us ship info and then wait the order delivery after payment, we will supply track number immediately when pack sent out

we experienced on shipping, we can promise free reshipping if seized by custom unfortunately.

 

Payment: T/T, , Bitcoin

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how to order

email or message us that includes your order like format below:

product A   100g

product B   10vials

 

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