CasNo.124858-35-1,Nadifloxacin,(124858-35-1) Suppliers

1 Gram	Negotiable

Min.Order :1 Gram
Purity: 99% purity
Payment Terms : T/T,Other

Keywords

NDFX 124858-35-1 99% purity

Quick Details

Appearance:White to yellow crystalline solid
Application:API
PackAge:According to the need to packing
ProductionCapacity:100|Kilogram|Month
Storage:sealed,dry,low temperature
Transportation:air,sea and courier

Superiority:

Nadifloxacin Basic information

Abstract Acne Treatment Antibacterial Activity Pharmacokinetics Drug resistance Application References
Product Name:   Nadifloxacin
Synonyms:   NDFX;Nadifiloxacin;NadifloxacinAPI;7-fluoro-8-(4-hydroxypiperidin-1-yl)-12-Methyl-4-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-2,5(13),6,8-tetraene-3-carboxylic acid;9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid;NADIFLOXACIN;9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic Acid;Acuati
CAS:   124858-35-1
MF:   C19H21FN2O4
MW:   360.38
EINECS:   638-863-6
Product Categories:   ACUATIM;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:   124858-35-1.mol

Details:

Nadifloxacin Chemical Properties
Melting point    245-2470C (dec)
Boiling point    624.9±55.0 °C(Predicted)
density    1.46±0.1 g/cm3(Predicted)
storage temp.    Sealed in dry,Store in freezer, under -20°C
pka   5.55±0.40(Predicted)
form    White to yellow crystalline solid.
Merck    14,6345
CAS DataBase Reference   124858-35-1(CAS DataBase Reference)
Safety Information
Toxicity   LD50 male, female mice and rats (mg/kg): 376.5, 420.6, 225.7, 240.5 i.v. (Hashimoto)

Chemical Properties   Off-White Crystalline Solid
Originator   Otsuka (Japan)
Uses   Fluorinated quinolone antibacterial (topical).
Uses   Fluorinated quinolone antibacterial (topical)
Uses   Calcium salt of polyacrylic acid crosslinked with divinyl glycol
Brand name   Acuatim
Pharmaceutical Applications   A lipophilic tricyclic fluorobenzoquinoline with a 4- hydroxylpiperinyl moiety at the C-8 position, formulated as a cream for topical use. It is active against many Grampositive bacteria involved in skin infections, including Propionibacterium acnes (MIC 0.25–2.0 mg/L), and Staph. aureus (MIC 0.015–2 mg/L). It appears to inhibit the generation of reactive oxygen species by neutrophils. The sodium salt is used as a 1% cream for use in acne vulgaris and cutaneous staphylococcal infections.