Factory direct sale 50-50-0

Details:

Estradiol Benzoate, Estradiol Valerate, Depofemin, 17α-Estradiol, Estriol, Dienogestrel, Medrogestone, ......

Estradiol benzoate

DMF available

Capacity: 1~2MT per Year 

CAS: 50-50-0

Molecule Formula: C25H28O3

Molecule Weight: 376.49

Molecule Structure: 

Other Name: 

3-Benzoyloxy-17β-estrol; EstradiolBenzoate (AS); EstradiolBenzoate,Powder,BP; 17-Estradiol-d33-Benzoate; (8R,9S,13S,14S,17S)-17-hydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenChemicalbookanthren-3-ylbenzoate; Estra-1,3,5(10)-triene-3,17-diol(17b)-3-benzoate;EstradiolBenzoate

Estradiol benzoate Usage And Synthesis

Chemical Properties White solid

Uses antiacne, antineoplastic

Uses Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the tr eatment of lesions produced by diminution of bodily production of estrogens.

Definition ChEBI: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.

Clinical Use Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.

Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.

Safety Profile Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Human reproductive effects by intramuscular route: menstrual cycle changes and disorders. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.