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Serratiopeptidase 37312-62-2 Serratiopeptidase Powder
Xi'an Kono Chem Co., Ltd., founded in 2014, is a holding enterprise of Hongkong Pioneer Biotech Group. It is an export-oriented manufacturing enterprise supported by the Ministry of Commerce.
Kono Chem is located in Xi'an, Shaanxi Province, equipped with a number of engineers in pharmaceutical, nutrition, bioengineerting, commited themselves to create products that meeet customers' requirements. At present, Kono's main products cover pharmaceutical, food, cosmetics, scientific research.
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1. Introduction
Serrapeptase powder is produced by a beneficial bacterium called Serratia marcescens, which lives in the guts of silkworms. When the silkworm becomes an imago, it uses the powerful action of this enzyme to break down the cocoon so that it can escape from the cocoon.
2. Main functions
2.1 Anti-inflammatory and repercussive
Serrapeptase powder can reduce capillary permeability induced by histamine, bradykinin and serotonin, decompose abnormal secretions and proteins; promote the absorption of decomposed products through blood and lymph, thereby improving the circulation of inflammatory lesions and eliminating swelling. For nasal congestion, runny nose and other symptoms; swollen throat, swollen tonsils, swollen lymph nodes and other signs.
2.2 Enhance the efficacy of antibiotics
It can significantly improve the efficacy of antibiotics on bacterial colony biofilm, and can inhibit the formation of bacterial colony biofilm, thereby promoting the penetration of antibiotics to the lesion site and enhancing the antibacterial effect.
2.3 Dissolving phlegm and purulent
By changing the viscosity and elasticity of the sputum, it can clear the secretions of the lung bronchus, which can effectively make the viscous sputum that is not easy to be eliminated through the decomposition of serrapeptase to become thinner, easy to drain, and promote airway patency.
3. Applications
Serrapeptase powder is mainly used in pharmaceutical and healthcare products.
4. Flow Chart
Inoculate the Serratia marcescens LL-413 strain into the enzyme production medium→28~32℃, 200~250r/min fermentation for 20~42h→dry cell concentration is 2.67~9.40g/L→serrapeptase activity Fermentation broth of 360.0~1505U/mL → centrifugation → removal of bacterial cells → salting out → dialysis → freeze drying → serrapeptase
5. Quality Standard
According to Enterprise Standard
Items |
Specifications |
Results |
Appearance |
Light grey powder |
Complies |
Odor & Taste |
Characteristic |
Characteristic |
Loss on drying |
≤7.0% |
4.25% |
Identifiable activity |
Positive for Serratiopeptidase Activity |
Complies |
Serratiopeptidase activity |
≥2200 SPU/mg |
2430 SPU/mg |
Heavy Metals |
≤10ppm |
<10ppm |
Pb |
≤3ppm |
<3ppm |
As |
≤1ppm |
<1ppm |
Hg |
≤0.1ppm |
<0.1ppm |
Cd |
≤1ppm |
<1ppm |
Microbiological |
||
Total Bacteria Count |
≤3,000 CFU/g |
<10CFU/g |
Coliform Bacteria (CFU/g) |
≤30 CFU/g |
<10CFU/g |
Molds and Yeasts |
≤100 CFU/g |
<10CFU/g |
E. coli |
Absent |
Not detected |
Salmonella |
Absent |
Not detected |
Staphylococcus aureus |
Absent |
Not detected |
Conclusion: |
The product complies with Enterprise Standard. |
6. Method of Analysis
MOA is available upon request.
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