CasNo.1968-05-4,China Biggest Factory & Manufacturer supply 3,3'-Diindolylmethane (DIM) 200MT/Year,(1968-05-4) Suppliers

500 Kilogram	FOB Price:USD 1.0000 -2.0000

3,3'-Diindolylmethane 1968-05-4 1968-05-4

3,3'-Diindolylmethane Basic information

Product Name:	3,3'-Diindolylmethane
Synonyms:	3,3'-Diindolylmethane(DIM);Di(1H-indol-3-yl);Plant Indole;3,3'-DIINDOLYLMETHANE, >=98% (HPLC);3,3'-METHYLENEBIS-1H-INDOLE;3,3'-METHYLENEBISINDOLE;3,3'-METHYLENEDIINDOLE;3,3'-DIINDOLYLMETHANE
CAS:	1968-05-4
MF:	C17H14N2
MW:	246.31
EINECS:	100-201-5
Product Categories:	Inhibitors;Pharmaceutical intermediates;Gene Regulation;Gene Regulation and Expression;Alkaloid;Antitumor Agents;Aromatic Compounds;Building Blocks;C13 to C27;Cancer Research;Cell Biology;Cell Signaling and Neuroscience;Chemical Synthesis;Enzyme Inhibitors;Indoles and derivatives;IndoleDerivative;Indoline & Oxindole;Indoles;Simple Indoles;Heterocyclic Building Blocks;Nutrition Research;Phytochemicals by Chemical Classification
Mol File:	1968-05-4.mol

3,3'-Diindolylmethane Chemical Properties

Melting point	167 °C
Boiling point	230 °C(Press: 0.01 Torr)
density	1.271±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform (Sparingly), Methanol (Slightly)
pka	16.91±0.30(Predicted)
form	Off-white powder.
CAS DataBase Reference	1968-05-4(CAS DataBase Reference)

Safety Information

MSDS Information

3,3'-Diindolylmethane Usage And Synthesis

Chemical Properties	Solid
Uses	apoptosis inducer
Uses	An antineoplastic agent that activates Chk 2 and cytochrome p450
Uses	3,3′-Diindolylmethane may be used as a model substrate to analyze the role of 3,3′-diindolylmethane in inducing apoptosis in human cancer cells.
General Description	3,3′-Diindolylmethane, a dimer of indole-3-carbinol, is a component of cruciferous vegetables. It is known to exhibit anticancer effects.
Biochem/physiol Actions	Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol. It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells. DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor. The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system.

3,3'-Diindolylmethane Preparation Products And Raw materials

Preparation Products

3,3'-Diindolylmethane Basic information

Product Name:	3,3'-Diindolylmethane
Synonyms:	3,3'-Diindolylmethane(DIM);Di(1H-indol-3-yl);Plant Indole;3,3'-DIINDOLYLMETHANE, >=98% (HPLC);3,3'-METHYLENEBIS-1H-INDOLE;3,3'-METHYLENEBISINDOLE;3,3'-METHYLENEDIINDOLE;3,3'-DIINDOLYLMETHANE
CAS:	1968-05-4
MF:	C17H14N2
MW:	246.31
EINECS:	100-201-5
Product Categories:	Inhibitors;Pharmaceutical intermediates;Gene Regulation;Gene Regulation and Expression;Alkaloid;Antitumor Agents;Aromatic Compounds;Building Blocks;C13 to C27;Cancer Research;Cell Biology;Cell Signaling and Neuroscience;Chemical Synthesis;Enzyme Inhibitors;Indoles and derivatives;IndoleDerivative;Indoline & Oxindole;Indoles;Simple Indoles;Heterocyclic Building Blocks;Nutrition Research;Phytochemicals by Chemical Classification
Mol File:	1968-05-4.mol

3,3'-Diindolylmethane Chemical Properties

Melting point	167 °C
Boiling point	230 °C(Press: 0.01 Torr)
density	1.271±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform (Sparingly), Methanol (Slightly)
pka	16.91±0.30(Predicted)
form	Off-white powder.
CAS DataBase Reference	1968-05-4(CAS DataBase Reference)

Safety Information

MSDS Information

3,3'-Diindolylmethane Usage And Synthesis

Chemical Properties	Solid
Uses	apoptosis inducer
Uses	An antineoplastic agent that activates Chk 2 and cytochrome p450
Uses	3,3′-Diindolylmethane may be used as a model substrate to analyze the role of 3,3′-diindolylmethane in inducing apoptosis in human cancer cells.
General Description	3,3′-Diindolylmethane, a dimer of indole-3-carbinol, is a component of cruciferous vegetables. It is known to exhibit anticancer effects.
Biochem/physiol Actions	Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol. It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells. DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor. The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system.