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China Biggest Factory & Manufacturer supplyRetinylaldehyde (Retinal) 50MT/Year
China Biggest Factory & Manufacturer supplyRetinylaldehyde (Retinal) 50MT/Year
China Biggest Factory & Manufacturer supplyRetinylaldehyde (Retinal) 50MT/Year
China Biggest Factory & Manufacturer supplyRetinylaldehyde (Retinal) 50MT/Year
China Biggest Factory & Manufacturer supplyRetinylaldehyde (Retinal) 50MT/Year

China Biggest Factory & Manufacturer supplyRetinylaldehyde (Retinal) 50MT/Year

Min.Order / FOB Price:Get Latest Price

50 Kilogram

FOB Price:USD 1.0000 -2.0000
  • Min.Order :50 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Retinylaldehyde Retinal 116-31-4

Quick Details

  • Appearance:white powder
  • Application:chemicals industry
  • PackAge:25KG/Drum
  • ProductionCapacity:20|Metric Ton|Month
  • Storage:2-8°C
  • Transportation:By air /Sea/ coruier

Superiority:

ALL-TRANS-RETINAL Basic information
Product Name: ALL-TRANS-RETINAL
Synonyms: 2,4,6,8-Nonatetraenal, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-;2,4,6,8-Nonatetraenal, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-;all-E-Retinal;all-trans-retina;All-trans-Retinaldehyde;alpha-Retinene;Axerophthal;E-Retinal
CAS: 116-31-4
MF: C20H28O
MW: 284.44
EINECS: 204-135-8
Product Categories: Vitamins;Aldehydes;Antitumor Agents;Building Blocks;C13-C60;Cancer Research;Carbonyl Compounds;Chemical Synthesis;Cofactor;Gene Regulation;Isoprenoid;Metabolic Pathways;Metabolites and Cofactors on the Metabolic Pathways Chart;Metabolomics;Intermediates & Fine Chemicals;Pharmaceuticals;Retinoids;Nutrition Research;Organic Building Blocks;Vitamin A
Mol File: 116-31-4.mol
ALL-TRANS-RETINAL Structure
 
ALL-TRANS-RETINAL Chemical Properties
Melting point  61-63°C
Boiling point  366.92°C (rough estimate)
density  1.0083 (rough estimate)
refractive index  1.4500 (estimate)
storage temp.  -20°C
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form  powder
color  yellow
Water Solubility  <70mg/L(25 ºC)
Stability: Hygroscopic, Light Sensitive, Temperature Sensitive
CAS DataBase Reference 116-31-4(CAS DataBase Reference)
EPA Substance Registry System Retinal (116-31-4)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22-38
Safety Statements  22-36/37
WGK Germany  3
RTECS  VH6407000
HS Code  29122990
MSDS Information
Provider Language
SigmaAldrich English
 
ALL-TRANS-RETINAL Usage And Synthesis
Chemical Properties Yellow Powder
Uses Corotenoid component of the visual pigments. All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase.
Uses retinaldehyde is a mild retinoid credited with increasing epidermal thickness without producing erythema.
Uses All trans-Retinal has been used:
  • in optogenetic experiments
  • in electrophysiological experiment
  • to study the effect of AKR1B10 (aldo-keto reductase (AKR) superfamily member) on the conversion of retinal to retinol in the airway epithelium
  • in decidual transformation of human endometrial stromal cells
Definition ChEBI: A retinal in which all four exocyclic double bonds have E- (trans-) geometry.
Synthesis Reference(s) Tetrahedron Letters, 29, p. 419, 1988 DOI: 10.1016/S0040-4039(00)80111-2
General Description

All trans-Retinal is one of the major derivatives of vitamin A group. A variety of food serves as a source of vitamin A. It is predominant in liver and among the brightly colored vegetables.
Biochem/physiol Actions All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells. Retinal isomers are also chromophores that bind to opsins, a family of G-protein-linked transmembrane proteins, to form photosensitive receptors in visual and nonvisual systems. All-trans retinal is a potent photosensitizer.
Purification Methods The aldehyde is separated from retinol by column chromatography on water-deactivated alumina. Elute with 1-2% acetone in hexane, or on TLC plates of silica gel G and using the same eluting solvent. It crystallises from pet ether or n-hexane as yellow-orange crystals, and the UV in hexane has max at 373nm (A1cm 1% 1,548) and 368nm ( 48,000). It is an irritant and is light sensitive. Store it in sealed ampoules under N2. The semicarbazone forms yellow crystals from CHCl3/Et2O or EtOH, m 199-201o(dec). The 9-cis-isomer [514-85-2] and the 13-cis-isomer [472-86-6] [max at 375nm ( 1,250) in EtOH] are also available commercially. [Beilstein 7 III 1742.]
 
ALL-TRANS-RETINAL Preparation Products And Raw materials
Raw materials Vitamin A-->EC 1.1.1.1
Preparation Products 9-CIS-RETINAL

 

Details:

ALL-TRANS-RETINAL Basic information
Product Name: ALL-TRANS-RETINAL
Synonyms: 2,4,6,8-Nonatetraenal, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-;2,4,6,8-Nonatetraenal, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-;all-E-Retinal;all-trans-retina;All-trans-Retinaldehyde;alpha-Retinene;Axerophthal;E-Retinal
CAS: 116-31-4
MF: C20H28O
MW: 284.44
EINECS: 204-135-8
Product Categories: Vitamins;Aldehydes;Antitumor Agents;Building Blocks;C13-C60;Cancer Research;Carbonyl Compounds;Chemical Synthesis;Cofactor;Gene Regulation;Isoprenoid;Metabolic Pathways;Metabolites and Cofactors on the Metabolic Pathways Chart;Metabolomics;Intermediates & Fine Chemicals;Pharmaceuticals;Retinoids;Nutrition Research;Organic Building Blocks;Vitamin A
Mol File: 116-31-4.mol
ALL-TRANS-RETINAL Structure
 
ALL-TRANS-RETINAL Chemical Properties
Melting point  61-63°C
Boiling point  366.92°C (rough estimate)
density  1.0083 (rough estimate)
refractive index  1.4500 (estimate)
storage temp.  -20°C
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form  powder
color  yellow
Water Solubility  <70mg/L(25 ºC)
Stability: Hygroscopic, Light Sensitive, Temperature Sensitive
CAS DataBase Reference 116-31-4(CAS DataBase Reference)
EPA Substance Registry System Retinal (116-31-4)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22-38
Safety Statements  22-36/37
WGK Germany  3
RTECS  VH6407000
HS Code  29122990
MSDS Information
Provider Language
SigmaAldrich English
 
ALL-TRANS-RETINAL Usage And Synthesis
Chemical Properties Yellow Powder
Uses Corotenoid component of the visual pigments. All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase.
Uses retinaldehyde is a mild retinoid credited with increasing epidermal thickness without producing erythema.
Uses All trans-Retinal has been used:
  • in optogenetic experiments
  • in electrophysiological experiment
  • to study the effect of AKR1B10 (aldo-keto reductase (AKR) superfamily member) on the conversion of retinal to retinol in the airway epithelium
  • in decidual transformation of human endometrial stromal cells
Definition ChEBI: A retinal in which all four exocyclic double bonds have E- (trans-) geometry.
Synthesis Reference(s) Tetrahedron Letters, 29, p. 419, 1988 DOI: 10.1016/S0040-4039(00)80111-2
General Description

All trans-Retinal is one of the major derivatives of vitamin A group. A variety of food serves as a source of vitamin A. It is predominant in liver and among the brightly colored vegetables.
Biochem/physiol Actions All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells. Retinal isomers are also chromophores that bind to opsins, a family of G-protein-linked transmembrane proteins, to form photosensitive receptors in visual and nonvisual systems. All-trans retinal is a potent photosensitizer.
Purification Methods The aldehyde is separated from retinol by column chromatography on water-deactivated alumina. Elute with 1-2% acetone in hexane, or on TLC plates of silica gel G and using the same eluting solvent. It crystallises from pet ether or n-hexane as yellow-orange crystals, and the UV in hexane has max at 373nm (A1cm 1% 1,548) and 368nm ( 48,000). It is an irritant and is light sensitive. Store it in sealed ampoules under N2. The semicarbazone forms yellow crystals from CHCl3/Et2O or EtOH, m 199-201o(dec). The 9-cis-isomer [514-85-2] and the 13-cis-isomer [472-86-6] [max at 375nm ( 1,250) in EtOH] are also available commercially. [Beilstein 7 III 1742.]
 
ALL-TRANS-RETINAL Preparation Products And Raw materials
Raw materials Vitamin A-->EC 1.1.1.1
Preparation Products 9-CIS-RETINAL

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