Chymotrypsin Powder...

Chymotrypsin Powder Bulk Quantity with Low Price
Chymotrypsin Powder Bulk Quantity with Low Price
Chymotrypsin Powder Bulk Quantity with Low Price

Chymotrypsin Powder Bulk Quantity with Low Price

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 45.0000 -50.0000

  • Min.Order :1 Kilogram
  • Purity: 300USP U/mg 2000USP U/mg
  • Payment Terms : L/C,T/T

Keywords

Chymotrypsin Powder 9004-07-3 α-Chymotrypsin

Quick Details

  • Appearance:White powder
  • Application:pharmaceutical industry
  • PackAge:25kg/drum
  • ProductionCapacity:3000|Kilogram|Month
  • Storage:cool & dry place
  • Transportation:by sea/air

Superiority:

Xi'an Kono Chem Co., Ltd., founded in 2014, is a holding enterprise of Hongkong Pioneer Biotech Group. It is an export-oriented manufacturing enterprise supported by the Ministry of Commerce. 

Kono Chem is located in Xi'an, Shaanxi Province, equipped with a number of engineers in pharmaceutical, nutrition, bioengineerting, commited themselves to create products that meeet customers' requirements. At present, Kono's main products cover pharmaceutical, food, cosmetics, scientific research. 


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Details:

1. Introduction

Chymotrypsin powder is a proteolytic enzyme extracted from bovine pancreas. There are many kinds of chymotrypsin, in addition to α type, there are β, γ, δ, π, ε, etc., among which α type chymotrypsin is the most stable one.

Chymotrypsin powder

 

2. Main Functions

2.1 Chymotrypsin can improve tissue permeability, inhibit inflammation, dissolve exudative and necrotic tissue, etc., thus improving acne symptoms. In some experiments, α-chymotrypsin 4000U + amikacin sulfate injection 2ml was injected into the cyst, and the total effective rate was 94.74%. Acne was treated by direct injection of α-chymotrypsin 5mg plus normal saline 2ml , 3 to 7 days as a course of treatment , 84 nodular cystic acnes were treated , 71 were cured and 13 were improved .

Chymotrypsin treat acne

2.2 Treatment of infertility

At present, it has been found that there are many factors involved in the semen liquefaction process, of which enzymes are the most important, α-chymotrypsin is an endopeptidase, which can significantly shorten the semen liquefaction time and reduce its viscosity, but has no effect on sperm motility. obvious impact. The clinical trial used α-chymotrypsin combined with intrauterine insemination for the treatment of infertility. 114 times of artificial insemination were performed on 38 patients with infertility, and 23 cases were pregnant.

a-chymotrypsin treat infertility

2.3 Treat ganglion cyst

Ganglion cyst is a cystic mass near the joint. There are many treatment methods. The traditional intracystic injection drug is hydrocortisone acetate, but it is easy to recur. The use of alpha-chymotrypsin in the treatment of ganglion cysts is mainly based on the action of alpha-chymotrypsin, a proteolytic enzyme that dissolves pus to thin it, dissolves blood clots and necrotic tissue, and eliminates cellulose caused by the inflammatory process Precipitation promotes the growth of granulation tissue, but has no effect on normal tissue.

Chymotrypsin treat ganglion cyst

 

2.4 Treat other diseases

It can also be used to treat many other diseases like chronic pharyngitis, pelvic inflammatory disease, lumbar disc herniation, herpetic stomatitis, severe pneumonia, chronic skin ulcers.

 

3. Applications

It is clinically used for wound healing after general trauma or surgery, anti-inflammatory, preventing local edema, blood accumulation, sprain hematoma, local swelling after breast surgery, otitis media, rhinitis, etc.; It is also used in combination with trypsin as a broad-spectrum anti-inflammatory drug. As an auxiliary drug for antibiotics and bactericidal drugs, it is widely used in animal medicine and animal health care.

Chymotrypsin application 1               Chymotrypsin application 2

             

4. Flow Chart

Bovine pancreas → leaching with sulfuric acid at 0°C → salting out of leaching solution → dissolving salted out in cold distilled water → adjusting pH with sulfuric acid → adjusting pH with ammonium sulfate and sodium hydroxide → crystallization → repeated dissolution → recrystallization → chymotrypsin Crystallization → activation → salting out → dialysis → drying → chymotrypsin

5. Quality Standard 

According to Enterprise Standard

Items

Specifications

Results

Appearance

White powder

White powder

Loss on drying

≤5.0%

3.0%

Redisue on ignition

≤5.0%

2.9%

Limit of Trypsin

No purple color develops within 3 minutes

Complies

Assay  

≥300 USP units/mg (calculated on the dried basis)

310 USP u/g

Microbiological limits

Total Plate Count

≤1000cfu/g

<1000cfu/g

Total Yeast & Mold

≤100cfu/g

<100cfu/g

E.Coli.

Negative

Not detected

Salmonella

Negative

Not detected

Conclusion

The product complies with enterprise standard and USP standard.

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