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1,6-Hexanediol 1,6-Hexanediol 629-11-8
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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research. Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products. Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation. We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.
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Product information
1,6-Hexanediol Basic information |
Product Name: | 1,6-Hexanediol |
Synonyms: | HEXANE-1,6-DIOL;HEXAMETHYLENE GLYCOL;HDO(R);1,6-DIHYDROXYHEXANE;1,6-HEXANEDIOL;1,6-HDO;1,6-HEXYLENE GLYCOL;HDO 1,6-Hexanediol Flakes |
CAS: | 629-11-8 |
MF: | C6H14O2 |
MW: | 118.17 |
EINECS: | 211-074-0 |
Product Categories: | Industrial/Fine Chemicals;HDO;amine series;Building Blocks;Organic solvents;Organic synthesis intermediates.plasticizer;alpha,omega-Alkanediols;alpha,omega-Bifunctional Alkanes;Monofunctional & alpha,omega-Bifunctional Alkanes;Optimization Reagents;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Polyols;Protein Structural Analysis;X-Ray Crystallography;629-11-8 |
Mol File: | 629-11-8.mol |
1,6-Hexanediol Chemical Properties |
Melting point | 38-42 °C (lit.) |
Boiling point | 250 °C (lit.) |
density | 0.96 |
vapor pressure | 0.53 mm Hg ( 20 °C) |
refractive index | 1.457 |
Fp | 215 °F |
storage temp. | Store below +30°C. |
solubility | H2O: 0.1 g/mL, clear, colorless |
pka | 14.87±0.10(Predicted) |
form | Waxy Flakes |
color | White |
PH | 7.6 (900g/l, H2O, 20℃) |
explosive limit | 6.6-16%(V) |
Water Solubility | 500 g/L |
λmax | λ: 260 nm Amax: 0.1 λ: 280 nm Amax: 0.1 |
Sensitive | Hygroscopic |
Merck | 14,4690 |
BRN | 1633461 |
InChIKey | XXMIOPMDWAUFGU-UHFFFAOYSA-N |
CAS DataBase Reference | 629-11-8(CAS DataBase Reference) |
NIST Chemistry Reference | 1,6-Hexanediol(629-11-8) |
EPA Substance Registry System | 1,6-Hexanediol (629-11-8) |
Safety Information |
Risk Statements | 36/37/38 |
Safety Statements | 36/37-24/25-23 |
WGK Germany | 1 |
RTECS | MO2100000 |
Autoignition Temperature | 608 °F |
TSCA | Yes |
HS Code | 29053980 |
Hazardous Substances Data | 629-11-8(Hazardous Substances Data) |
Toxicity | LD50 orally in rats: 3.73 g/kg (Carpenter) |
MSDS Information |
Provider | Language |
---|---|
Hexamethylene glycol | English |
ACROS | English |
SigmaAldrich | English |
ALFA | English |
1,6-Hexanediol Usage And Synthesis |
Description | 1,6-Hexanediol is a waxy hygroscopic solid compound that is white in colour. The compound is a linear diol that contains two primary hydroxyl groups that are located at the terminal. 1,6-Hexanediol’s linear hydrocarbon chain enables the compound to have enhanced hardness and flexibility of polyesters. Moreover, this property is utilized in the extending chains in polyurethanes. |
Preparation | 1,6-Hexanediol is produced by a propriety process that is based on BASF technology. Industrially, it is prepared by the hydrogenation of adipic acid. Conversely, in the laboratory, 1,6-Hexanediol can be synthesized by the reduction of adipic acid with lithium aluminum hydride. |
Uses and Applications | Polyurethanes 1,6-Hexanediol is widely utilized in the manufacture of polyesterols such as sebacates, azelates, and adipates. These compounds are resistant to hydrolysis and have low glass transition temperature as well as high mechanical levels. 1,6-hexanediol is used as an ingredient in the preparation of a wide range of tailor-made products for numerous specialty and standard applications. In Acrylics 1,6-hexanediol is utilized as an ingredient in the manufacture of the bifunctional hexanediol diacrylate which is a monomer that is normally used in conjunction with other acrylic monomers as a reactive diluent for decorative coatings and printing inks. In Adhesives Urethanes and co-terephthalates that are based on 1,6-hexanediol provide faster better tack properties and crystallization. Due to its low glass transition property, 1,6-hexanediol offers high flexibility as well as excellent adhesive properties. Other Uses 1,6-hexanediol is incorporated into the production of other compounds used in polymeric thickeners, sizing agents, plasticizers for polyvinyl chloride, pesticides, and surfactants dyestuffs as a flexible building block. |
Safety | 1,6-hexanediol is a no-irritating to the skin. However, it can be irritative to the respiratory tract and mucous membrane. 1,6-hexanediol vapours or dust cause irritation to the eye. Severe eye exposure may cause conjunctivitis, iritis, and diffuse corneal opacity. |
Chemical Properties | white waxy flakes |
Uses | Solvent, intermediate for high polymers (nylon, polyesters), coupling agent, coil coating. |
Uses | 1,6-Hexanediol is used in polymer synthesis such as polyester, polyurethane and nylon. It is used as an intermediate to adhesives, acrylics and dyestuffs. Further, it is employed in gasoline refining and pharmaceutical production. |
Uses | 1,6-Hexanediol can be used for a variety of applications such as:
|
Definition | ChEBI: A diol that is hexane substituted by hydroxy groups at positions 1 and 6. |
Synthesis Reference(s) | Tetrahedron Letters, 34, p. 243, 1993 DOI: 10.1016/S0040-4039(00)60557-9 |
Hazard | Toxic by ingestion. |
Purification Methods | Fractionally crystallise it from its melt or from water. Distil it in vacuo. [Beilstein 1 IV 2556.] |
1,6-Hexanediol Preparation Products And Raw materials |
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