China Biggest Factory manufacturer supply L-Alanine CAS 56-41-7

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L-Alanine Basic information Description References Product Name: L-Alanine Synonyms: (S)-2-Aminopropanoic acid;(s)-2-aminopropanoicacid;Aspartic Acid Impurity 6;Tenofovir Impurity 80;(S)-2-Aminopropansαure;(S)-2-Aminopropionsαure;2-Aminopropanoic acid;2-Aminopropanoicacid CAS: 56-41-7 MF: C3H7NO2 MW: 89.09 EINECS: 200-273-8 Product Categories: Amino Acids;Alphabetical Listings;AStable Isotopes;Stable Isotopes;GABA/Glycine receptor;bio-chemical;food additive;food flavor;alanine;amino acid;chemicals;food additives;organic acids;pharmaceutical intermediate;Food & Feed ADDITIVES;Amino Acids;Alanine [Ala, A];Amino Acids and Derivatives;alpha-Amino Acids;Biochemistry;Nutritional Supplements;L-Amino Acids;amino Mol File: 56-41-7.mol   L-Alanine Chemical Properties Melting point  314.5 °C alpha  14.5 º (c=10,6N HCl,dry sub.) Boiling point  212.9±23.0 °C(Predicted) density  1,432 g/cm3 FEMA  3818 | DL-ALANINE refractive index  1.4650 (estimate) storage temp.  2-8°C solubility  H2O: 100 mg/mL pka 2.34(at 25℃) form  powder color  White to almost white PH 5.5-6.5 (100g/l, H2O, 20℃) optical activity [α]20/D +14.0±1°, c = 5% in 5 M HCl Water Solubility  166.5 g/L (25 ºC) λmax λ: 260 nm Amax: ≤0.03 λ: 280 nm Amax: ≤0.02 Merck  14,204 BRN  1720248 Stability: Stable. Incompatible with strong oxidizing agents. InChIKey QNAYBMKLOCPYGJ-REOHCLBHSA-N CAS DataBase Reference 56-41-7(CAS DataBase Reference) NIST Chemistry Reference Alanine(56-41-7) EPA Substance Registry System L-Alanine (56-41-7)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  24/25-36-26 WGK Germany  3 RTECS  AY2990000 F  10 TSCA  Yes HazardClass  IRRITANT HS Code  29224995 Hazardous Substances Data 56-41-7(Hazardous Substances Data) MSDS Information Provider Language Ala English ACROS English SigmaAldrich English ALFA English   L-Alanine Usage And Synthesis Description Alanine (also called 2-aminopropanoic acid, α-aminopropanoic acid) is an amino acid that helps the body convert the simple glucose into energy and eliminate excess toxins from the liver. Amino acids are the building blocks of important proteins and are key to building strong and healthy muscles. Alanine belongs to non-essential amino acids, which can be synthesized by the body. However, all amino acids may become essential if the body is unable to produce them. People with low-protein diets or eating disorders, liver disease, diabetes, or genetic conditions that cause Urea Cycle Disorders (UCDs) may need to take alanine supplements to avoid a deficiency.  Alanine has been shown to help protect cells from being damaged during intense aerobic activity when the body cannibalizes muscle protein to produce energy. Alanine is used to support prostate health and is important for the regulation of insulin. L-alanine is the L-enantiomer of alanine. L-alanine is utilized in clinical nutrition as a component for parenteral and enteral nutrition. L-alanine plays a key role in transferring nitrogen from tissue sites to the liver. L-Alanine is widely used as nutrition supplements, as sweetener and flavor enhancer in the food industry, as flavor enhancer and preservative in the beverage industry, as intermediate for medicine manufacturing in pharmaceutical, as nutritional supplement and sour corrective agent in agriculture/animal feed, and as intermediate in manufacturing of various organic chemicals. References [1] //www.ajiaminoscience.com/products/manufactured_products/l-amino_acids/L-Alanine.aspx [2] //www.foodchemadditives.com/applications-uses/1500 [3] //www.vitaminstuff.com/amino-acid-alanine.html Description L-Alanine is a non-essential amino acid. It is produced by direct β-decarboxylation of L-aspartate by L-aspartate β-decarboxylase or transamination of pyruvate in the glucose-alanine cycle and is a precursor for gluconeogenesis. Dysregulation of L-alanine metabolism is associated with various disease states, including diabetes, metabolic syndrome, ketotic hypoglycemia, and acquired acute lactic acidosis. Chemical Properties A white, odorless powder having a sweet taste Chemical Properties White crystalline powder Occurrence Natural constituent of protein in plants and animals; found in apple, beef, carob, pea, soybean, wine and zucchini Uses L-Alanine plays a vital role in glucose-alanine cycle between tissue and liver. It is used for protein construction as well as involved in the metabolism of tryptophan and vitamin pyridoxine. It provides energy for muscles and central nervous system in order to strengthen the immune system. It helps in the metabolism of sugars and organic acids, and enhances the germination rates of Bacillus subtilis spores. It also displays a cholesterol-reducing effect in animals. Uses Alanine is an amino acid that can act as a skin-conditioning agent. It is usually used in combination with other amino acids. Definition ChEBI: The L-enantiomer of alanine. Preparation Anthrobacter oxydans HAP-1 hyper produces DL-alanine in a nongrowth-associated manner. General Description L-Alanine, a non-essential amino acid, is produced enzymatically from L-aspartate using aspartate β-decarboxylase. It is the smallest among all the amino acids. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Biochem/physiol Actions L-Alanine is a nonessential amino acid, which is highly concentrated in muscle. It is a key player in the Glucose-Alanine cycle, which enables the removal of pyruvate and glutamate from muscle to the liver. Once in the liver, glucose is regenerated from pyruvate and returned to the muscle while glutamate ultimately participates in the urea cycle to form urea. The Glucose-Alanine cycle aides to conserve ATP in muscle for muscle contraction, while the energy burden of gluconeogenesis is imposed upon the liver. Alanine inhibits pyruvate kinase to regulate gluconeogenesis and glycolysis in order to maintain glucose homeostasis during starvation. Alanine prevents hepatic autophagy. Alanine formation is a result of transamination of glutamate and pyruvate. Safety Profile Mutation data reported. When heated to decomposition it emits toxic fumes of Nox Purification Methods Crystallise alanine from H2O or aqueous EtOH, i.e. crystallise it from 25% EtOH in water, or recrystallise it from 62.5% EtOH, wash it with EtOH and dry it to constant weight in vacuo over P2O5. [Gutter & Kegeles J Am Chem Soc 75 3893 1953, Walsh J Biol Chem 264 2394 1989.] 2,2'-Iminodipropionic acid is a likely impurity. [Beilstein 4 IV 2480. 2481.]   L-Alanine Preparation Products And Raw materials Raw materials Activated carbon-->Hexamethylenetetramine-->Propionic acid-->Potassium Phosphate Monobasic-->Α-PROTEIN-->HYDROGEN CYANIDE-->Fumaric acid-->Casein-->L-Aspartic acid-->β-Alanine-->Cyanamide-->Agar-->Sodium propionate-->Ammonium bromide-->2-Chloropropionic acid-->5 KG YEAST EXTRACT SERVABACTERPOWDER-->Meat extracts, beef-->2-Bromopropionic acid Preparation Products DL-Tryptophan-->Metalaxyl-->Ramipril-->Pyridoxine hydrochloride-->5-Ethoxy-4-methyloxazole-->D(-)-allo-Threonine-->5-Bromouracil-->Ethyl 2-aminopropanoate hydrochloride-->S-(+)-2-Amino-1-propanol-->3-Aminopropanol

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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