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Hot Sales!!!!!!!!!+China Biggest Manufacturer supply Deoxyarbutin

Hot Sales!!!!!!!!!+China Biggest Manufacturer supply Deoxyarbutin

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 1.0000 -2.0000

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Deoxyarbutin Deoxyarbutin 53936-56-4

Quick Details

  • Appearance:white powder
  • Application:Pharm chemicals industry
  • PackAge:25KG/Drum
  • ProductionCapacity:200|Metric Ton|Month
  • Storage:2-8°C
  • Transportation:By air /Sea/ coruier

Superiority:

                                PRODUCT DETAILS                           


Deoxyarbutin Basic information
Uses
Product Name: Deoxyarbutin
Synonyms: Deoxyarbutin;Tetrahydropyranyloxyphenol;4-(TETRAHYDRO-2H-2-PYRANYLOXY)PHENOL;4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenol;Phenol,4-[(tetrahydro-2H-pyran-2-yl)oxy]-;Deoxyarbutin 4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenol;4-[(2-Tetrahydropyranyl)oxy]phenol;LGB-D ARBUTIN
CAS: 53936-56-4
MF: C11H14O3
MW: 194.23
EINECS: 1308068-626-2
Product Categories: Inhibitors;Cosmetics
Mol File: 53936-56-4.mol
Deoxyarbutin Structure
 
Deoxyarbutin Chemical Properties
Melting point  88-89 °C(Solv: ligroine (8032-32-4))
Boiling point  349.8±32.0 °C(Predicted)
density  1.174
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
pka 10.10±0.15(Predicted)
form  Solid
color  White to Off-White
Stability: Hygroscopic
 
Safety Information
MSDS Information
 
Deoxyarbutin Usage And Synthesis
Uses Deoxyarbutin acts as a skin whitening agent through the inhibition of tyrosinase. A safer alternative to the use of hydroquinone and arbutin.
Description Deoxyarbutin is a tyrosinase inhibitor (IC50 = 17.5 μM for mushroom tyrosinase). It reduces melanin content in isolated dark human melanocytes when used at a concentration of 1.56 μM. Topical administration of deoxyarbutin (5%) induces skin lightening in human skin mouse xenograft models. Deoxyarbutin also inhibits proliferation of B16/F10 murine melanoma cells (EC50 = 39.56 μM). It induces apoptosis and halts the cell cycle at the S phase in B16/F10 cells when used at a concentration of 50 μM. Deoxyarbutin (50 mg/kg) reduces tumor growth in a B16/F10 murine melanoma model.
Uses Deoxyarbutin acts as a skin whitening agent through the inhibition of tyrosinase. A safer alternative to the use of hydroquinone and arbutin.
 
Deoxyarbutin Preparation Products And Raw materials


                                Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

 

Our Factories production lines

                                                   Our Factories R&D ability

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Details:

                                                       Product information


Deoxyarbutin Basic information
Uses
Product Name: Deoxyarbutin
Synonyms: Deoxyarbutin;Tetrahydropyranyloxyphenol;4-(TETRAHYDRO-2H-2-PYRANYLOXY)PHENOL;4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenol;Phenol,4-[(tetrahydro-2H-pyran-2-yl)oxy]-;Deoxyarbutin 4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenol;4-[(2-Tetrahydropyranyl)oxy]phenol;LGB-D ARBUTIN
CAS: 53936-56-4
MF: C11H14O3
MW: 194.23
EINECS: 1308068-626-2
Product Categories: Inhibitors;Cosmetics
Mol File: 53936-56-4.mol
Deoxyarbutin Structure
 
Deoxyarbutin Chemical Properties
Melting point  88-89 °C(Solv: ligroine (8032-32-4))
Boiling point  349.8±32.0 °C(Predicted)
density  1.174
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
pka 10.10±0.15(Predicted)
form  Solid
color  White to Off-White
Stability: Hygroscopic
 
Safety Information
MSDS Information
 
Deoxyarbutin Usage And Synthesis
Uses Deoxyarbutin acts as a skin whitening agent through the inhibition of tyrosinase. A safer alternative to the use of hydroquinone and arbutin.
Description Deoxyarbutin is a tyrosinase inhibitor (IC50 = 17.5 μM for mushroom tyrosinase). It reduces melanin content in isolated dark human melanocytes when used at a concentration of 1.56 μM. Topical administration of deoxyarbutin (5%) induces skin lightening in human skin mouse xenograft models. Deoxyarbutin also inhibits proliferation of B16/F10 murine melanoma cells (EC50 = 39.56 μM). It induces apoptosis and halts the cell cycle at the S phase in B16/F10 cells when used at a concentration of 50 μM. Deoxyarbutin (50 mg/kg) reduces tumor growth in a B16/F10 murine melanoma model.
Uses Deoxyarbutin acts as a skin whitening agent through the inhibition of tyrosinase. A safer alternative to the use of hydroquinone and arbutin.
 
Deoxyarbutin Preparation Products And Raw materials

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