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China Biggest Manufacturer factory sales 4-Hexyl-1,3-benzenediol CAS 136-77-6
China Biggest Manufacturer factory sales 4-Hexyl-1,3-benzenediol CAS 136-77-6
China Biggest Manufacturer factory sales 4-Hexyl-1,3-benzenediol CAS 136-77-6
China Biggest Manufacturer factory sales 4-Hexyl-1,3-benzenediol CAS 136-77-6
China Biggest Manufacturer factory sales 4-Hexyl-1,3-benzenediol CAS 136-77-6

China Biggest Manufacturer factory sales 4-Hexyl-1,3-benzenediol CAS 136-77-6

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1000 Kilogram

FOB Price:USD 1.0000 -2.0000

  • Min.Order :1000 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

4-Hexyl-1,3-benzenediol 4-Hexyl-1,3-benzenediol 136-77-6

Quick Details

  • Appearance:white powder
  • Application:Pharm chemicals industry
  • PackAge:25KG/Drum
  • ProductionCapacity:20|Metric Ton|Month
  • Storage:2-8°C
  • Transportation:By air /Sea/ coruier

Superiority:

                                PRODUCT DETAILS                           

4-Hexyl-1,3-benzenediol Basic information
Uses
Product Name: 4-Hexyl-1,3-benzenediol
Synonyms: 1-(2',4'-Dihydroxyphenyl)hexane;1-(2,4-Dihydroxyphenyl)hexane;1,3-Benzenediol, 4-hexyl-;1,3-Benzenediol,4-Hexyl-1,3-benzenediol;1,3-Dihydroxy-4-Hexylbenzene;1,3-Dihydroxy-4-n-hexylbenzene;4-hexylresourcinol;Adrover
CAS: 136-77-6
MF: C12H18O2
MW: 194.27
EINECS: 205-257-4
Product Categories: Miscellaneous;136-77-6
Mol File: 136-77-6.mol
4-Hexyl-1,3-benzenediol Structure
 
4-Hexyl-1,3-benzenediol Chemical Properties
Melting point  65-67 °C (lit.)
Boiling point  333-335 °C (lit.)
density  1.0010 (rough estimate)
refractive index  1.5050 (estimate)
Fp  >100°C
storage temp.  2-8°C
solubility  chloroform: 50 mg/mL, clear
pka pKa 9.1 (Uncertain)
form  Powder and/or Chunks
color  White to pale orange or pale pink
PH 7.7 (0.5g/l, H2O, 20℃)
Water Solubility  0.05 g/100 mL (18 ºC)
Merck  14,4712
BRN  2048312
Stability: Stable. Incompatible with acid chlorides, acid anhydrides, oxidizing agents.
InChIKey WFJIVOKAWHGMBH-UHFFFAOYSA-N
CAS DataBase Reference 136-77-6(CAS DataBase Reference)
NIST Chemistry Reference Hexylresorcinol(136-77-6)
EPA Substance Registry System 4-Hexylresorcinol (136-77-6)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22-36/37/38-20/21/22
Safety Statements  26-36-24/25
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  VH1575000
TSCA  Yes
HS Code  29072900
Hazardous Substances Data 136-77-6(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 550 mg/kg
MSDS Information
Provider Language
4-Hexyl-1,3-benzenediol English
SigmaAldrich English
ACROS English
ALFA English
 
4-Hexyl-1,3-benzenediol Usage And Synthesis
Uses p-Hexylresorcinol shows antiimnflammatory activity acting on the human 5-LO (5-Lipoxygenase) proinflammatory enzyme.
Chemical Properties slightly red powder
Uses anthelmintic, topical antiseptic
Uses 4-Hexylresorcinol is an inhibitor of transglutaminase-2 in KB cells. Studies indicate that 4-Hexylresorcinol reduces DNA oxidative damage in human lymphocytes. is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections. is a substituted phenol with bactericidal, antihelminthic and potential antineoplastic activities. The combination of 4-Hexylresorcinol and Cisplatin has been shown to inhibit tumor growth, cell growth, and KB cell viability.
Uses

4-Hexylresorcinol is used as the starting material to synthesize a potent immune suppressor, celastramycin A. It is a precursor to prepare resorcinol-sn-glycerol derivatives, that exhibit high affinity for cannabinoid type 1 receptor. It can also be incorporated as a linker while building catenanes.

General Description Pale-yellow viscous liquid (that becomes solid on standing at room temperature) or a peach colored powder. Pungent faintly fatty odor. Sharp astringent taste.
Air & Water Reactions Insoluble in water.
Reactivity Profile 4-Hexyl-1,3-benzenediol may be sensitive to prolonged exposure to light. Incompatible with acid chlorides, acid anhydrides and oxidizing agents .
Hazard Irritant to respiratory tract and skin, concentrated solutions are vesicant.
Fire Hazard Flash point data for 4-Hexyl-1,3-benzenediol are not available. 4-Hexyl-1,3-benzenediol is probably combustible.
Clinical Use 4-Hexylresorcinol, or “hexylresorcinol,” is a white crystallinesubstance with a faint phenolic odor. When appliedto the tongue it produces a sensation of numbness. It isfreely soluble in alcohol but only slightly soluble in water(1–20,000 parts). Hexylresorcinol is an effective antiseptic,possessing both bactericidal and fungicidal properties.The phenol coefficient of hexylresorcinol against S. aureusis 98. As is typical for alkylated phenols, hexylresorcinolpossesses surfactant properties. The compound also haslocal anesthetic activity. Hexylresorcinol is formulatedinto throat lozenges because of its local anesthetic and antisepticproperties. These preparations are probably of littlevalue. Hexylresorcinol (in the concentration in thelozenge) is probably not antiseptic, and the local anestheticproperty can anesthetize the larynx, causing temporarylaryngitis.
 
4-Hexyl-1,3-benzenediol Preparation Products And Raw materials
Raw materials Zinc chloride-->Resorcinol-->Hexanoic acid-->4-Hexanoylresorcinol-->2-Hexenyl bromide-->o-Cresol-->Hexanoyl chloride
 
Undecylenoyl Phenylalanine Preparation Products And Raw materials
 

                                      Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

 

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                                                       Product information

4-Hexyl-1,3-benzenediol Basic information
Uses
Product Name: 4-Hexyl-1,3-benzenediol
Synonyms: 1-(2',4'-Dihydroxyphenyl)hexane;1-(2,4-Dihydroxyphenyl)hexane;1,3-Benzenediol, 4-hexyl-;1,3-Benzenediol,4-Hexyl-1,3-benzenediol;1,3-Dihydroxy-4-Hexylbenzene;1,3-Dihydroxy-4-n-hexylbenzene;4-hexylresourcinol;Adrover
CAS: 136-77-6
MF: C12H18O2
MW: 194.27
EINECS: 205-257-4
Product Categories: Miscellaneous;136-77-6
Mol File: 136-77-6.mol
4-Hexyl-1,3-benzenediol Structure
 
4-Hexyl-1,3-benzenediol Chemical Properties
Melting point  65-67 °C (lit.)
Boiling point  333-335 °C (lit.)
density  1.0010 (rough estimate)
refractive index  1.5050 (estimate)
Fp  >100°C
storage temp.  2-8°C
solubility  chloroform: 50 mg/mL, clear
pka pKa 9.1 (Uncertain)
form  Powder and/or Chunks
color  White to pale orange or pale pink
PH 7.7 (0.5g/l, H2O, 20℃)
Water Solubility  0.05 g/100 mL (18 ºC)
Merck  14,4712
BRN  2048312
Stability: Stable. Incompatible with acid chlorides, acid anhydrides, oxidizing agents.
InChIKey WFJIVOKAWHGMBH-UHFFFAOYSA-N
CAS DataBase Reference 136-77-6(CAS DataBase Reference)
NIST Chemistry Reference Hexylresorcinol(136-77-6)
EPA Substance Registry System 4-Hexylresorcinol (136-77-6)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22-36/37/38-20/21/22
Safety Statements  26-36-24/25
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  VH1575000
TSCA  Yes
HS Code  29072900
Hazardous Substances Data 136-77-6(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 550 mg/kg
MSDS Information
Provider Language
4-Hexyl-1,3-benzenediol English
SigmaAldrich English
ACROS English
ALFA English
 
4-Hexyl-1,3-benzenediol Usage And Synthesis
Uses p-Hexylresorcinol shows antiimnflammatory activity acting on the human 5-LO (5-Lipoxygenase) proinflammatory enzyme.
Chemical Properties slightly red powder
Uses anthelmintic, topical antiseptic
Uses 4-Hexylresorcinol is an inhibitor of transglutaminase-2 in KB cells. Studies indicate that 4-Hexylresorcinol reduces DNA oxidative damage in human lymphocytes. is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections. is a substituted phenol with bactericidal, antihelminthic and potential antineoplastic activities. The combination of 4-Hexylresorcinol and Cisplatin has been shown to inhibit tumor growth, cell growth, and KB cell viability.
Uses

4-Hexylresorcinol is used as the starting material to synthesize a potent immune suppressor, celastramycin A. It is a precursor to prepare resorcinol-sn-glycerol derivatives, that exhibit high affinity for cannabinoid type 1 receptor. It can also be incorporated as a linker while building catenanes.

General Description Pale-yellow viscous liquid (that becomes solid on standing at room temperature) or a peach colored powder. Pungent faintly fatty odor. Sharp astringent taste.
Air & Water Reactions Insoluble in water.
Reactivity Profile 4-Hexyl-1,3-benzenediol may be sensitive to prolonged exposure to light. Incompatible with acid chlorides, acid anhydrides and oxidizing agents .
Hazard Irritant to respiratory tract and skin, concentrated solutions are vesicant.
Fire Hazard Flash point data for 4-Hexyl-1,3-benzenediol are not available. 4-Hexyl-1,3-benzenediol is probably combustible.
Clinical Use 4-Hexylresorcinol, or “hexylresorcinol,” is a white crystallinesubstance with a faint phenolic odor. When appliedto the tongue it produces a sensation of numbness. It isfreely soluble in alcohol but only slightly soluble in water(1–20,000 parts). Hexylresorcinol is an effective antiseptic,possessing both bactericidal and fungicidal properties.The phenol coefficient of hexylresorcinol against S. aureusis 98. As is typical for alkylated phenols, hexylresorcinolpossesses surfactant properties. The compound also haslocal anesthetic activity. Hexylresorcinol is formulatedinto throat lozenges because of its local anesthetic and antisepticproperties. These preparations are probably of littlevalue. Hexylresorcinol (in the concentration in thelozenge) is probably not antiseptic, and the local anestheticproperty can anesthetize the larynx, causing temporarylaryngitis.
 
4-Hexyl-1,3-benzenediol Preparation Products And Raw materials
Raw materials Zinc chloride-->Resorcinol-->Hexanoic acid-->4-Hexanoylresorcinol-->2-Hexenyl bromide-->o-Cresol-->Hexanoyl chloride

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