Top suppliers Factory sales Cialis tadanafil CAS no. 171596-29-5

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Tadanafil reference:
The average onset time of Tadanafil is 16-30 minutes. The plasma concentration reaches the peak 2-8 hours after taking it, and the half-life is 44-112 hours. The half-life is prolonged in renal insufficiency. Even after 5 days, the concentration of Tadanafil can still be measured in plasma. The clinical report showed that the effective rate reached 83% after taking silex, and the reported dosage was 10 ~ 20 mg. Its advantages are small side effects and long duration, which can have obvious effects in about twoorthree days.
After oral administration, it was absorbed rapidly, and the median time after taking the medicine reached the upper limit of the average. The plasma concentration (Cmax) was observed. The bioavailability of this product after oral administration is not clear The absorption rate and degree of tadalafil are not affected by food, so this product can be taken with or without food. The time of taking medicine (morning or evening) has no clinically significant effect on the absorption rate and degree. The average distribution volume is about 63 liters, indicating that tadalafil is distributed into the tissue. At the treatment concentration, 94% of tadalafil in plasma binds to protein. Protein binding is not affected by renal function damage. In healthy subjects, the average clearance rate of tadalafil was 2 5l/hr, with an average half-life of 17.5 hours Tadalafil is mainly excreted in the form of inactive metabolites, mainly from feces (about 61% dose), and a small part from urine (about 36% dose)

Side effects of Tadanafil:
Some users will have adverse reactions, generally including dry mouth (sex and thirst), back muscle pain, muscle weakness, headache, slight flushing on the face, accelerated heart rate, and excessive use will lead to frequent headache, hyperactivity, and non sleepiness.
Tadanafil should be used with caution in the following patients: patients prone to abnormal erection (such as sickle cell anemia, multiple myeloma or leukemia), or patients with abnormal vaginal anatomy. Those with hypertension, heart disease, diabetes, anemia and renal insufficiency are forbidden. Long term use may cause dependence on drugs, and should not be compatible with alkaline drugs.

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Hebei Youze biotechnology Co., Ltd. has a registered capital of 1 million yuan and is one of the most dynamic foreign trade companies in the Chinese market. We have a pharmaceutical raw material production plant and a reagent R&D center. We now have the most complete product line. In addition, we have developed and produced tens of thousands of reagents. We also have the business of custom synthesis of various organic compounds as a supplement. We can synthesize almost all chemicals. Our goal is to survive by quality and develop by credit.