China Biggest Manufacturer factory sales Erythorbic Acid CAS 89-65-6

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Erythorbic Acid Basic information Product Name: Erythorbic Acid Synonyms: 2,3-didehydro-d-erythro-hexono-1,4-lactone;FEMA 2410;ISOASCORBIC ACID;ISOVITAMIN C;3-keto-d-erythro-hexonicacigamma-lactone;araboascorbicacid;d-arabino-ascorbicacid;d-erythro-3-ketohexonicacidlactone CAS: 89-65-6 MF: C6H8O6 MW: 176.12 EINECS: 201-928-0 Product Categories: Food additive;Water Ttreatment Chemicals;Sugar Acids;Vitamin Derivatives;Biochemistry;Sugars;Food and Feed Additive;Vitamins Mol File: 89-65-6.mol   Erythorbic Acid Chemical Properties Melting point  169-172 °C (dec.) (lit.) alpha  -17.25 º (c=10, H2O 25 ºC) Boiling point  227.71°C (rough estimate) density  1.3744 (rough estimate) FEMA  2410 | ERYTHROBIC ACID refractive index  -17.5 ° (C=10, H2O) storage temp.  2-8°C solubility  H2O: 0.1 g/mL, clear, colorless to very faintly yellow form  Crystals or Crystalline Powder pka 4.09±0.10(Predicted) color  White to slightly yellow optical activity [α]25/D 16.8°, c = 2 in H2O Water Solubility  1g/10mL Merck  14,5126 BRN  84271 Stability: Stable. Combustible. Incompatible with chemically active metals, aluminium, zinc, copper, magnesium, strong bases, strong oxidizing agents. InChIKey CIWBSHSKHKDKBQ-JLAZNSOCSA-N CAS DataBase Reference 89-65-6(CAS DataBase Reference) EPA Substance Registry System Isoascorbic acid (89-65-6)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-24/25 WGK Germany  2 RTECS  KF3015000 TSCA  Yes HS Code  29329990 Hazardous Substances Data 89-65-6(Hazardous Substances Data) MSDS Information Provider Language 2,3-Didehydro-D-erythro-hexono-1,4-lactone English SigmaAldrich English ACROS English ALFA English   Erythorbic Acid Usage And Synthesis Chemical Properties Erythorbic acid occurs as a white or slightly yellow-colored crystals or powder. It gradually darkens in color upon exposure to light. Uses Antioxidant (industrial and food), especially in brewing industry, reducing agent in photography. Uses Erythorbic Acid is a food preservative that is a strong reducing agent (oxygen accepting) which functions similarly to antioxidants. In the dry crystalline state it is nonreactive, but in water solutions it reacts readily with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant. During preparation, dissolving and mixing should incorporate a minimum amount of air, and storage should be at cool temperatures. It has a solubility of 43 g/100 ml of water at 25°c. One part is equivalent to one part ascorbic acid and equivalent to one part sodium erythorbate. It is used to control oxidative color and flavor deterioration in fruits at 150–200 ppm. It is used in meat curing to speed and control the nitrite curing reaction and prolong the color of cured meat at levels of 0.05%. Uses Erythorbic Acid is used as a food additive as an antimicrobial and antioxidative agent. Production Methods Erythorbic acid is synthesized by the reaction between methyl 2- keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose, and produced from Penicillium spp. Biotechnological Production Yeasts and other fungi synthesize the C5 sugar acid D-erythroascorbic acid which shares structural and physicochemical properties with Asc. D-erythroascorbic acid serves similar protective functions in these microorganisms as Asc does in plants and animals, including the scavenging of reactive oxygen species. The biosynthesis of D-erythroascorbic acid starts from D-arabinose obtained by the microorganism from decaying plant material. D-arabinose, presumably in its 1,4-furanosidic isomeric form, is oxidized by NAD(P)+ specific dehydrogenases to D-arabinono-1,4-lactone, which is further oxidized to D-erythroascorbic acid by D-arabinono-1,4-lactone oxidase. Resting cells of Saccharomyces cerevisiae can synthesize Asc from L-galactose, L-galactono-1,4-lactone, or L-gulono- 1,4-lactone via the pathway naturally used for D-erythroascorbic acid. Pharmaceutical Applications Erythorbic acid is a stereoisomer of L-ascorbic acid, and is used as an antioxidant in foods and oral pharmaceutical formulations. It has approximately 5% of the vitamin C activity of L-ascorbic acid. Safety Erythorbic acid is widely used in food applications as an antioxidant. It is also used in oral pharmaceutical applications as an antioxidant. Erythorbic acid is generally regarded as nontoxic and nonirritant when used as an excipient. Erythorbic acid is readily metabolized and does not affect the urinary excretion of ascorbic acid. The WHO has set an acceptable daily intake of erythorbic acid and its sodium salt in foods at up to 5 mg/kg body-weight. storage Erythorbic acid should be stored in an airtight container, protected from light, in a cool, dry place. Purification Methods Crystallise D(-)-isoascorbic acid from H2O, EtOH or dioxane. is at 245nm with 7,500 (EtOH). [Reichstein et al. Helv max Chim Acta 17 510, 516 1934, Heslop et al. J Chem Soc 225 1944, Beilstein 18 III/IV 3037, 18/5 V 26.] Incompatibilities Erythorbic acid is incompatible with chemically active metals such as aluminum, copper, magnesium, and zinc. It is also incompatible with strong bases and strong oxidizing agents. Regulatory Status GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral concentrate and tablets).   Erythorbic Acid Preparation Products And Raw materials Raw materials Sodium methoxide-->D(+)-Glucose-->Starch-->Calcium gluconate-->Gluconic acid-->Sodium erythorbate-->Zinc silicate-->Trimethacrylate-->methyl 2-oxogluconate-->arabinosone-->dehydroerythorbic acid-->2-oxogluconic acid-->Alanine, ethyl ester (9CI)

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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