China Biggest Manufacturer factory sales 3-Phenylpropionic Acid CAS 501-52-0

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3-Phenylpropionic acid Basic information Description Preparation Uses Product Name: 3-Phenylpropionic acid Synonyms: Benzenepropionic acid;benzenepropionicacid;hydrocinnamic;Phenylpropanoic acid;propanoicacid,3-phenyl-;propionicacid,3-phenyl-;Benyl propionic acid;Hydrocinamic acid CAS: 501-52-0 MF: C9H10O2 MW: 150.17 EINECS: 207-924-5 Product Categories: Aromatics;Aloe Vera;Building Blocks;C9;Carbonyl Compounds;Carboxylic Acids;Pharmaceutical Intermediates;Aromatic Propionic Acids;Cinnamic acid;Organic acids;Chemical Synthesis;Nutrition Research;Organic Building Blocks;Phytochemicals by Plant (Food/Spice/Herb);501-52-0 Mol File: 501-52-0.mol   3-Phenylpropionic acid Chemical Properties Melting point  45-48 °C (lit.) Boiling point  280 °C (lit.) density  1.071 g/mL at 25 °C (lit.) FEMA  2889 | 3-PHENYLPROPIONIC ACID refractive index  1.5408 (estimate) Fp  >230 °F storage temp.  Sealed in dry,Room Temperature solubility  ethanol: soluble50mg/mL, clear, colorless to faintly yellow form  Liquid pka 4.66(at 25℃) Specific Gravity 1.071 color  Clear yellow to yellow-green Water Solubility  Soluble in water JECFA Number 646 Merck  14,4784 BRN  907515 InChIKey XMIIGOLPHOKFCH-UHFFFAOYSA-N CAS DataBase Reference 501-52-0(CAS DataBase Reference) NIST Chemistry Reference 3-Phenylpropanoic acid(501-52-0) EPA Substance Registry System Hydrocinnamic acid (501-52-0)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-37/39-26 WGK Germany  3 RTECS  DA8600000 TSCA  Yes HS Code  29163900 MSDS Information Provider Language beta-Phenylpropionic acid English ACROS English SigmaAldrich English ALFA English   3-Phenylpropionic acid Usage And Synthesis Description 3-Phenylpropionic acid is a carboxylic acid that belongs to the class of phenylpropanoids. Also referred as hydrocinnamic acid, the chemical is a white crystalline solid with a sweet fatty smell of rose musk cinnamon at room temperature. 3-Phenylpropionic acid is soluble in both water and alcohol. It is widely used in food additives, cosmetics, and pharmaceuticals. Preparation Hydrogenation of cinnamic acid is used in the preparation of 3-Phenylpropionic acid. Initially, the chemical was prepared by reduction with sodium amalgam in water by electrolysis. Uses Food Industry 3-Phenylpropionic acid is utilized in the food industry as a preservative as well as to maintain the original quality of aroma of frozen foods. It is also used for flavoring and restoring original color to food. 3-Phenylpropionic acid is added to shelved foods to prevent microorganisms from deteriorating the food. It also acts as an antioxidant to prolong the life of foodstuff in shelves. 3-Phenylpropionic acid is also used as a food sweetener. 3-Phenylpropionic acid acts as an emulsifier as it can keep water and oil mixtures separated. 3-Phenylpropionic acid can be added in food for technological reasons in wide range such as processing, manufacturing, packaging, treatment, transportation, and storage. Cosmetics 3-Phenylpropionic acid is used in beautifying products such as bath gels, detergent powders, and fabric softeners as it gives a floral scent. It is also used as a flavour for mouthwashes and toothpastes. Chemical Properties white to off-white crystalline mass, powder or crystals and/or chunk Chemical Properties 3-Phenylpropionic acid has a faint, sweet odor, somewhat balsamic and coumarin-like with a mildly sweet-sour, vanilla-like taste. Occurrence Reported found in raspberry, guava fruit, Vitis vinifera L., papaya, strawberry fruit, cinnamon, cassia leaf, cheddar cheese, cocoa, beer, cognac, white wine, red wine, special wine, rose apple, mushroom, cloudberry, Boletus edulis, fresh mango, licorice and labdanum. Uses Used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid. Uses Hydrocinnamic acid was used in the synthesis of three medium-chain acyl-Coenzyme A′s i.e. 3-phenylpropionyl-CoA from mixed anhydrides of fatty acids. Uses Hydrocinnamic acid is inhibitor of carboxypeptidase. Hydrocinnamic acid was used in the synthesis of three medium-chain acyl-Coenzyme A s i.e. 3-phenylpropionyl-CoA from mixed anhydrides of fatty acids. Definition ChEBI: A monocarboxylic acid that is propionic acid substituted at position 3 by a phenyl group. Preparation By reduction of cinnamic acid using sodium amalgam. Synthesis Reference(s) Tetrahedron Letters, 29, p. 5599, 1988 DOI: 10.1016/S0040-4039(00)80822-9 General Description Hydrocinnamic acid forms complexes with uranium(VI) and has been investigated in aqueous solution by attenuated total reflection fourier transform infrared spectroscopy. Hydrocinnamic acids are the major rhizospheric compounds with known growth regulatory activity. Purification Methods Crystallise the acid from *benzene, CHCl3 or pet ether (b 40-60o). Dry it in a vacuum. [Beilstein 9 H 508.]   3-Phenylpropionic acid Preparation Products And Raw materials Raw materials Nickel-->Amalgam sodium Preparation Products Iopanoic acid-->3-(4-NITRO-PHENYL)-PROPIONALDEHYDE-->Bedaquiline (fuMarate)-->Cyclohexanepropionic acid-->(3aR,4R,5R,6aS)-5-(Benzoyloxy)hexahydro-4-[(1E)-3-oxo-5-phenyl-1-pentenyl]-2H-cyclopenta[b]furan-2-one-->USP7-IN-1-->(S)-(+)-2-Phenylpropionic acid

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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