The world Biggest Manufacturer factory sales Ethylenebis(oxyethylenenitrilo)tetraacetic acid/ EGTA CAS 67-42-5

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Ethylenebis(oxyethylenenitrilo)tetraacetic acid Basic information Description Product Name: Ethylenebis(oxyethylenenitrilo)tetraacetic acid Synonyms: 3,6-DIOXAOCTAMETHYLENEDINITRILOTETRAACETIC ACID;1,2-bis(2-dicarboxymethylaminoethoxy)ethane;12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-9-dioxa-3;6,9-Dioxa-3,12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-;9-Dioxa-3,12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-6;ebonta;ethylenedioxybis(ethyleneamino)tetraaceticacid;ETHYLENE GLYCOL BIS-(BETA-AMINOETHYLETHER)-N,N,N',N'-TETRAACETIC CAS: 67-42-5 MF: C14H24N2O10 MW: 380.35 EINECS: 200-651-2 Product Categories: Analytical Chemistry;Chelating Reagents;Complexones;EDTA Analogs Mol File: 67-42-5.mol   Ethylenebis(oxyethylenenitrilo)tetraacetic acid Chemical Properties Melting point  241 °C (dec.)(lit.) Boiling point  507.99°C (rough estimate) density  1.2838 (rough estimate) refractive index  1.4590 (estimate) storage temp.  room temp solubility  0.1 M NaOH: 0.1 M at 20 °C, clear, colorless pka 1.47±0.10(Predicted) form  Crystalline Powder color  White Water Solubility  slightly soluble Merck  14,3529 BRN  1717370 CAS DataBase Reference 67-42-5(CAS DataBase Reference) EPA Substance Registry System Ethylenebis(oxyethylenenitrilo)tetraacetic acid (67-42-5)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  24/25-36-26 WGK Germany  2 RTECS  AH3760000 TSCA  Yes HS Code  29225000 Toxicity LD50 orally in Rabbit: 3587 mg/kg MSDS Information Provider Language Ethylenebis(oxyethylenenitrilo)tetraacetic acid English ACROS English SigmaAldrich English ALFA English   Ethylenebis(oxyethylenenitrilo)tetraacetic acid Usage And Synthesis Description Ethylenebis(oxyethylenenitrilo)tetraacetic acid is also named as Egtazic acid. It works as a chelating agent for the determination of calcium in the presence of magnesium. Chemical Properties White to slightly off-white powder Uses Pharmaceutic aid. EGTA. Uses Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid is a chelating agent used for making complexes, especially for calcium ions, which help to determine calcium in the presence of magnesium. It can be used experimentally for treating animals possessing cerium poisoning. It is useful in the separation of thorium from monazite. It also acts as a buffer and is used in protein purification. Uses A chelating agent useful for the determination of calcium in the presence of magnesium. Definition ChEBI: A diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively. Biological Activity Calcium chelator; protects against cell death caused by nitric oxide-induced calcium influx into nerve cells. Safety Profile Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. See also GLYCOL ETHERS. Purification Methods Dissolve EGTA in aqueous NaOH, precipitate it by adding aqueous HCl, wash it with water and dry at 100o in vacuo.[Beilstein 4 IV 217.]   Ethylenebis(oxyethylenenitrilo)tetraacetic acid Preparation Products And Raw materials Raw materials 1,8-Diamino-3,6-dioxaoctane-->Chloroacetic acid

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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