China Largest Manufacturer factory sales D-Mandelic Acid CAS 611-71-2

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Mandelic acid Basic information Product Name: Mandelic acid Synonyms: (R)-(-)-2-MANDELIC ACID;(R)-2-HYDROXY-2-PHENYLACETIC ACID;(R)-(-)-AMYGDALIC ACID;(R)-ALPHA-HYDROXYPHENYLACETIC ACID;R-(-)-ALPHA-HYDROXYPHENYLACETIC ACID;(R)-(-)-MANDELIC ACID;(R)-MANDELIC ACID;D-ALPHA-HYDROXYPHENYLACETIC ACID CAS: 611-71-2 MF: C8H8O3 MW: 152.15 EINECS: 210-276-6 Product Categories: Aromatics;Chiral Reagents;Chiral Compounds;Miscellaneous;Intermediates & Fine Chemicals;Pharmaceuticals;chiral;Analytical Chemistry;Carboxylic Acids (Chiral);Chiral Building Blocks;e.e. / Absolute Configuration Determination (NMR);Enantiomer Excess & Absolute Configuration Determination;for Resolution of Bases;Optical Resolution;FINE Chemical & INTERMEDIATES;Synthetic Organic Chemistry;Chiral Compound;Cosmetic Mol File: 611-71-2.mol   Mandelic acid Chemical Properties Melting point  131-133 °C(lit.) alpha  -150 º (c=2.5, H2O) Boiling point  214.6°C (rough estimate) density  1.1677 (rough estimate) refractive index  -153.5 ° (C=1, H2O) Fp  >190℃ storage temp.  Store below +30°C. solubility  109.8g/l soluble pka 3.37(at 25℃) form  Crystalline Powder, Crystals or Flakes color  White to slightly yellow-beige PH 3.34(1 mM solution);2.75(10 mM solution);2.22(100 mM solution); optical activity [α]25/D 151°, c = 1 in ethanol Water Solubility  It is partly soluble in water, freely soluble in isopropyl and ethyl alcohol. Sensitive  Light Sensitive BRN  2691094 Stability: Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents. InChIKey IWYDHOAUDWTVEP-SSDOTTSWSA-N CAS DataBase Reference 611-71-2(CAS DataBase Reference) EPA Substance Registry System Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)- (611-71-2)   Safety Information Hazard Codes  Xi Risk Statements  41-36/37/38 Safety Statements  22-24/25-36-26-39-37/39 WGK Germany  1 Hazard Note  Irritant/Light Sensitive TSCA  Yes HS Code  29181980 Toxicity LD50 orally in Rabbit: 5000 mg/kg MSDS Information Provider Language 2-Phenylglycolic acid English SigmaAldrich English ACROS English ALFA English   Mandelic acid Usage And Synthesis Chemical Properties white to light yellow crystal powde Uses Antiseptic (urinary). Uses (R)-(-)-Mandelic acid, is used as a antiseptic ingredient particularly against urinary tract infections.Mandelic acid and its derivatives are used to apply the dual activities as an antibacterial agent and as an antiaging agent. It is used as an intermediate for the synthesis of target molecules for other applications. Uses (R)-( )-Mandelic acid can be used: As a chiral acid in the separation of diastereomeric salts for the synthesis of chiral pyridoindole based building block. In the study of chiral acid selectivity of poly(3,4-ethylenedioxythiophene) (PEDOT) based chiral conducting polymers. Synthesis Reference(s) The Journal of Organic Chemistry, 33, p. 2565, 1968 DOI: 10.1021/jo01270a105 Synthetic Communications, 18, p. 2141, 1988 DOI: 10.1080/00397918808068285 General Description (R)-(-)-Mandelic acid, a chiral resolving agent, is also used as a building block to synthesize pharmaceutical drugs such as penicillin and cephalosporin. It can be synthesized from (R,S)-mandelonitrile with high yield and enantioselectivity using nitrilase enzyme. Purification Methods Purify the mandelic acids by recrystallisation from H2O, *C6H6 or CHCl3. [Roger J Chem Soc 2168 1932,Jamison & Turner J Chem Soc 611 1942.] They have solubilities in H2O of ca 11% at 25o. [Banks & Davies J Chem Soc 73 1938.] The S-benzylisothiuronium salts has m 180o (from H2O) and [] D 25 (+) and (-) 57o (c20, EtOH) [El Masri et al. Biochem J 68 199 1958]. [Beilstein 10 IV 564.]   Mandelic acid Preparation Products And Raw materials Raw materials (S)-(+)-O-Acetyl-L-mandelic acid-->Vinyl acetate Preparation Products 1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4R)-(9CI)

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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