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PRODUCT DETAILS
Calcium formate Basic information |
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Calcium formate Chemical Properties |
Melting point |
300 °C |
density |
2,02 g/cm3 |
storage temp. |
Inert atmosphere,Room Temperature |
solubility |
H2O: 1 M at 20 °C, clear, colorless |
form |
orthorhombic crystals |
Specific Gravity |
2.02 |
PH |
7.51(1 mM solution);7.92(10 mM solution);8.24(100 mM solution);8.47(1000 mM solution) |
Water Solubility |
SOLUBLE |
λmax |
λ: 260 nm Amax: ≤0.04
λ: 280 nm Amax: ≤0.03 |
Hydrolytic Sensitivity |
0: forms stable aqueous solutions |
Merck |
13,1670 |
BRN |
3624099 |
InChIKey |
CBOCVOKPQGJKKJ-UHFFFAOYSA-L |
CAS DataBase Reference |
544-17-2(CAS DataBase Reference) |
EPA Substance Registry System |
Formic acid, calcium salt (544-17-2) |
Provider |
Language |
Calcium formate |
English |
SigmaAldrich |
English |
ACROS |
English |
ALFA |
English |
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Calcium formate Usage And Synthesis |
Description |
Calcium formate is a white to almost white fine crystalline powder. It can be used an accelerator for the pozzolanic cement pastes. On the one hand, it shortens the initial and final setting times and increases the compressive strength and combined water content as well as gel/space ratio at all ages of hydration. On the other hand, it decreases the total porosity. It has been shown that it has a growth-promoting effect in weanling pigs challenged with E. coli, independently of their susceptibility to the intestinal adhesion of this strain. More importantly, calcium formate can be used as a nutrient supplement to the feed of young growing pigs or fattening poultry, further boosting the growth of animals and the feed utilization. At the same time, it causes a reduction of the occurrence of piglet diarrhea.
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Chemical Properties |
Calcium formate, Ca(HCOO)2, is the calcium salt of formic acid, HCOOH. It is also known as food additive E238 in food industry. The mineral form is very rare and called formicaite. It is known from a few boron deposits. It may be produced synthetically by reacting calcium oxide or calcium hydroxide with formic acid. |
Chemical Properties |
Calcium formate is white solid, solubility at 0 °C 13.90 g, at 40 °C 14.56 g, at 80 °C 15.22 g of anhydrous salt per 100 g saturated solution, formed by reaction of calcium carbonate or hydroxide and formic acid. Calcium formate, when heated with a calcium salt of a carboxylic acid higher in the series, yields an aldehyde. |
Uses |
Calcium Formate is Hydrophobic additives for construction materials.Formic Acid is used as a potential energy source in the preparation of fuel cells. Also used in chemical synthesis of various anti-inflammatory and anti-microbial agents. |
Uses |
Preservative for food, silage; as binder for fine-ore briquets; in drilling fluids and lubricants.
Calcium formate is an organic salt suitable for use in pig and poultry diets. It acts as a feedstock preservative and has an acidifying effect on the gastro-intestinal tract, which promotes good gut-health. The efficiency of pig and poultry feedstock digestion is dependent on the indigenous micro-organism concentration in the gastro-intestinal tract. With the approaching ban on the use of prophylactic antibiotics in animal feed as a means to control disease and promote growth, alternatives are needed to limit the proliferation of pathogenic bacteria in the gut which can impair feedstock digestion as well as cause enteric diseases such as E. Coli and Salmonella. Acidifiers such as calcium formate preserve the feedstock before consumption and lower the pH in the gastro-intestinal tract, creating unfavourable conditions for these bacteria to grow.
Calcium formate is used extensively in the leather industry as a masking agent in the chrome-tanning process. The addition of calcium formate to the tannage formulation promotes faster, more efficient penetration of the chrome in the leather. Calcium formate can also be used as a replacement for formic acid in the pickling operation. |
Reactions |
Calcium formate can be used to prepare solutions of other water-soluble formate salts. For example, the addition of nickel (II) sulfate to a solution of calcium formate results in the precipitation of insoluble calcium sulfate, leaving nickel (II) formate in solution:
Ca(OOCH)2 + NiSO1 → CaSO4 + Ni(OOCH)2
In a similar reaction, sulfuric acid reacts with calcium formate to provide low-cost solutions of formic acid:
Ca(OOCH)2 + H2 SO4 → CaSO4 + 2HCOOH
When heated, calcium formate decomposes to calcium carbonate and formaldehyde:
Ca(OOCH)2 → CaCO3 + HCHO
Calcium formate can be used as a low-cost reducing agent in the conversion of carboxylic acids to aldehydes. This process is an effective substitute for the troublesome Rosenmund reduction.
(RCOO)2Ca + (HCOO)2CA → 2RCH + 2CaCO3 |
Safety Profile |
Poison by intravenous route. Moderately toxic by ingestion. An eye irritant. When heated to decomposition it emits acrid smoke and fumes. See also CALCIUM COMPOUNDS. |
Purification Methods |
Recrystallise it from water (5mL/g) by partial evaporation in a desiccator. [Beilstein 2 IV 16.] |
Toxicity evaluation |
Calcium formate has a low order of toxicity. In rats, the acute oral LD50 is 2650mg/kg; by intravenous injection, the LD50 is 154mg/kg.
In a study with rats, calcium formate added to the drinking water at 0.2% for 3 years or 0.4% for 2 years didn't affect growth, fertility or function in up to 5 generations.
Calcium formate would be expected to be irritating to the eyes and skin. In case of eye contact, immediately flush the eyes with water for 15 minutes. Avoid prolonged or repeated exposure of the skin. |
References |
Heikal, Mohamed. "Effect of calcium formate as an accelerator on the physicochemical and mechanical properties of pozzolanic cement pastes." Cement & Concrete Research 34.6(2004):1051-1056.
Bosi, P, et al. "The influence of fat protection of calcium formate on growth and intestinal defense in Escherichia coli K88-challenged weanling pigs." Animal Feed Science & Technology 139.3–4(2007):170-185.
Bolze, Rudolf, et al. "Agent for increasing the performance of pigs and poultry." EP, EP0260391. 1988. |
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Calcium formate Preparation Products And Raw materials |
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Group profiles
Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research. Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products. Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation. We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.
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