fradizine 1401-69-0 98% purity
Tylosin Basic information
Product Name: Tylosin
Synonyms: TYLOCINE(R);TYLOSIN;fradizine;tylocine;Tylosine;TYLAN50;Tylosin (base and/or unspecified salts);N,N-Tylozine
CAS: 1401-69-0
MF: C46H77NO17
MW: 916.1
EINECS: 215-754-8
Product Categories:
Mol File: 1401-69-0.mol
Tylosin Chemical Properties
Melting point 135-137°C
alpha D25 -46° (c = 2 in methanol)
Boiling point 796.05°C (rough estimate)
density 1.1424 (rough estimate)
refractive index 1.5280 (estimate)
storage temp. Sealed in dry,2-8°C
pka pKa 7.73(H2O t = 25 I = 0.167) (Uncertain)
Water Solubility H2O: soluble 50 mg/mL
Stability: Solutions are stable at pH 4-9 (most stable at pH 7);
Below pH 4 tylosin B (desmycosin) is formed as a result of acid hydrolysis;
In neutral and alkaline pH – tylosin aldol (TAD) is formed together with polar degradation products of unknown identity;
When tylosin solution is exposed to daylight, a photodegradation product - isotylosin A (isoTA) is formed.
EPA Substance Registry System Tylosin (1401-69-0)
Safety Information
Hazard Codes Xn,N
Risk Statements 42/43-50
Safety Statements 36-61-45-36/37-22
HS Code 2941906000
Hazardous Substances Data 1401-69-0(Hazardous Substances Data)
Toxicity Tylosin base and its salts were shown to be of low acute oral toxicity with LD50 values in excess 5000 mg/kg bw in the rat and mouse and greater than 800 mg/kg bw in the dog.
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