China Largest Manufacturer factory sales N-Methylphthalimide CAS 550-44-7

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N-Methylphthalimide Basic information Product Name: N-Methylphthalimide Synonyms: 2-Methylisoindoline-1,3-dione;2-Methyl-1H-isoindole-1;Rivaroxaban Impurity F ( N-Methyl Phthalimide ) CAS No. 550-44-7;Imp. F:N-Methylphthalimide;Rivaroxaban impurity P1-B;Rivaroxaban N-Methylphthalimide Impurity;Rivaroxaban Impurity F ( N-Methyl Phthalimide );Rivaroxaban Impurity 20 CAS: 550-44-7 MF: C9H7NO2 MW: 161.16 EINECS: 208-982-4 Product Categories: intermediates;N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Phthalimides;Cyclic ImidesDerivatization Reagents;Carbonyl Compounds;Derivatization Reagents HPLC;API intermediates;Organic Building Blocks;UV-VIS Mol File: 550-44-7.mol   N-Methylphthalimide Chemical Properties Melting point  129-132 °C (lit.) Boiling point  286.05°C density  1.2443 (rough estimate) refractive index  1.4500 (estimate) storage temp.  Sealed in dry,Room Temperature solubility  DMSO (Slightly), Methanol (Slightly) pka -2.09±0.20(Predicted) form  Solid color  White to Off-White BRN  124428 CAS DataBase Reference 550-44-7(CAS DataBase Reference) NIST Chemistry Reference 1H-Isoindole-1,3(2H)-dione, 2-methyl-(550-44-7) EPA Substance Registry System 1H-Isoindole-1,3(2H)-dione, 2-methyl- (550-44-7)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-36 WGK Germany  1 RTECS  TI5602700 TSCA  Yes HazardClass  IRRITANT HS Code  29251900 MSDS Information Provider Language N-Methylphthalimide English SigmaAldrich English ALFA English   N-Methylphthalimide Usage And Synthesis Chemical Properties White powder Uses Photoreduction of N-methylphthalimide (NMP) with 2,3-dimethyl-2-butene h and the selective electroreduction of N-methylphthalimide to 3-hydroxy-2-methyl-isoindolin-1-one have been studied. Synthesis Reference(s) The Journal of Organic Chemistry, 44, p. 497, 1979 DOI: 10.1021/jo01318a005 General Description Photoreduction of N-methylphthalimide (NMP) with 2,3-dimethyl-2-butene has been studied. The selective electroreduction of N-methylphthalimide to 3-hydroxy-2-methyl-isoindolin-1-one in ionic liquids and phenol as a proton donor under silent and ultrasonic conditions has been reported. Single electron transfer (SET)-induced photochemical reaction of NMP with silyl enol ether has been investigated. Nitration of NMP is reported to afford “exclusively” 3-nitro-derivative. Purification Methods Recrystallise the imide from absolute EtOH or AcOH (m 134o). The IR has max at 1780 and 1380cm -1. [Beilstein 21 H 461, 21 III/IV 5030.]   N-Methylphthalimide Preparation Products And Raw materials Preparation Products N-Methyl-3-nitrophthalimide-->4-Nitro-N-methylphthalimide-->N-(Bromomethyl)phthalimide-->4-AMINO-N-METHYLPHTHALIMIDE Product Name: N-Cyclohexyl-3-aminopropanesulfonic acid Synonyms: N-Cyclohexyl-3-aMinopropanesulfonic acid (CAPS);CAPS, free acid;BRAND push-on cap for Technicon Analyzer;Push-on caps;BRAND combi-pack caps and seal for Transferpette;Seals;BRAND strip of 8 lids, for 96 tube rack;BRAND cap for UV-cuvette micro CAS: 1135-40-6 MF: C9H19NO3S MW: 221.32 EINECS: 214-492-1 Product Categories: Pharmaceutical Intermediates;buffer Mol File: 1135-40-6.mol   N-Cyclohexyl-3-aminopropanesulfonic acid Chemical Properties Melting point  >300 °C(lit.) density  1.1809 (rough estimate) refractive index  1.5250 (estimate) Fp  >110℃ storage temp.  room temp solubility  H2O: 0.5 M at 20 °C, clear form  Powder/Solid color  White Odor Odorless PH 3.0-7.0 (20℃, 0.5M in H2O) PH Range 3 - 7 pka 10.4(at 25℃) Water Solubility  9 g/100 mL (20 ºC) λmax λ: 260 nm Amax: ≤0.04 λ: 280 nm Amax: ≤0.04 Merck  14,1767 BRN  2835588 Stability: Stable. Incompatible with strong oxidizing agents. CAS DataBase Reference 1135-40-6(CAS DataBase Reference) EPA Substance Registry System 1-Propanesulfonic acid, 3-(cyclohexylamino)- (1135-40-6)   Safety Information Hazard Codes  Xi,Xn Risk Statements  36/38-36/37/38-22-20/21/22-40/22 Safety Statements  26-36/37/39-37/39-24/25-22-23-36 WGK Germany  3 RTECS  TZ6395000 F  34 TSCA  Yes HS Code  29213099 MSDS Information Provider Language 3-(Cyclohexylamino)-1-propanesulfonic acid English SigmaAldrich English ACROS English ALFA English   N-Cyclohexyl-3-aminopropanesulfonic acid Usage And Synthesis Chemical Properties White/clear crystalline powder Uses Biological buffer. Uses CAPS (N-cyclohexyl-3-aminopropanesulfonic acid) buffer salt is used to formulate CAPS buffer, a zwitterionic buffer that is useful in the range of pH 7.9-11.1. CAPS buffer is widely used in Western and immunoblotting experiments as well as protein sequencing and identification. Used in the electrotransfer of proteins to PVDF (sc-3723) or nitrocellulose membranes (sc-3718, sc-3724). The high pH of this buffer makes it useful for the transfer of proteins with a pI > 8.5. CAPS is not one of the original Good s buffers, although it has a similar structure to the other propanesulfonic acids and was selected as a highly water soluble buffering reagent with an optimum buffering pH of 10.4 and minimal reactivity with enzymes or proteins, minimal salt effects.   N-Cyclohexyl-3-aminopropanesulfonic acid Preparation Products And Raw materials Product Name: TAPS Synonyms: 3-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-PROPANESULFONIC ACID;3-[[TRIS(HYDROXYMETHYL)METHYL]AMINO]PROPANESULFONIC ACID;3-[N-TRIS-(HYDROXYMETHYL)METHYLAMINO]-PROPANESULPHONIC ACID;3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-1-propanesulfonic acid;[2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]AMINO)-1-PROPANESULFONIC ACID;TAPS;TAP;N-TRIS(HYDROXYMETHYL)METHYL-3-AMINOPROPANESULFONIC ACID CAS: 29915-38-6 MF: C7H17NO6S MW: 243.28 EINECS: 249-954-1 Product Categories: Biochemistry;Good's Buffers;API intermediates;Buffer Mol File: 29915-38-6.mol   TAPS Chemical Properties Melting point  230-235 °C (dec.) density  1.4290 (rough estimate) refractive index  1.6370 (estimate) Fp  110 °C storage temp.  Keep in dark place,Sealed in dry,Room Temperature solubility  H2O: 1 M at 20 °C, clear, colorless form  Solid pka 8.55; pKa (37°): 8.1; pKa2 (25°): 8.28 color  White Odor Odorless PH Range 7.7 - 9.1 Water Solubility  Soluble Merck  13,9148 BRN  2452420 Stability: Stable. Incompatible with strong oxidizing agents InChIKey YNLCVAQJIKOXER-UHFFFAOYSA-N CAS DataBase Reference 29915-38-6(CAS DataBase Reference) EPA Substance Registry System 1-Propanesulfonic acid, 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (29915-38-6)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-36-26 WGK Germany  3 TSCA  Yes HazardClass  IRRITANT HS Code  29221980 MSDS Information Provider Language 3-[[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-1-propanesulfonic acid English SigmaAldrich English ACROS English ALFA English   TAPS Usage And Synthesis Chemical Properties White/clear crystalline powder Uses A zwitterionic Good's Buffer   TAPS Preparation Products And Raw materials Product Name: MES sodium salt Synonyms: Natrium-4-morpholin-1-ylethylsulfonat;2-(N-Morpholino)ethanesulphonic acid sodium salt;4-Morpholine-1-ethanesulfonic acid sodium salt;MES sodium salt,99%;2-(N-Morpholino)ethanesulfonic acid sodium salt, 4-Morpholineethanesulfonic acid sodium salt;4-Morpholineethanesulfonic acid, sodium salt (1:1);Einecs 275-203-2;MES sodium salt,2-(N-Morpholino)ethanesulfonic acid sodium salt, 4-Morpholineethanesulfonic acid sodium salt CAS: 71119-23-8 MF: C6H12NNaO4S MW: 217.22 EINECS: 275-203-2 Product Categories: Pharmaceutical Raw Materials Mol File: 71119-23-8.mol   MES sodium salt Chemical Properties Melting point  >250 C (dec.) storage temp.  room temp solubility  H2O: 0.5 g/mL, clear, colorless form  Powder color  White PH Range 5.5 - 6.7 BRN  3765682 CAS DataBase Reference 71119-23-8(CAS DataBase Reference) EPA Substance Registry System 4-Morpholineethanesulfonic acid, sodium salt (71119-23-8)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  22-24/25-36-26 WGK Germany  1 HS Code  29349990 MSDS Information Provider Language SigmaAldrich English   MES sodium salt Usage And Synthesis Chemical Properties White powder Uses MES sodium salt is a buffering agent used in biological and biochemical research including plant cell culture. Uses MES sodium salt has been used: To achieve the required density and stretching of DNA fibers during melting of agarose plugs containing genomic DNA To equilibrate the Balch homogenizer chamber and to prevent sample hydrolysis before sample homogenization Uses MES Sodium is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity. MES Sodium is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components. Definition ChEBI: The organic sodium salt that is the sodium salt of 2-(N-morpholino)ethanesulfonic acid. General Description MES is one of the so-called "Good" buffers developed for biological applications. This product is BioPerformance certified (suitable for electrophoresis, tissue culture, and molecular biology applications. A buffer using MES free acid can be prepared by titrating the free acid with sodium hydroxide to the desired pH (pKa=±1). Alternatively, volumes of equimolar solutions of MES free acid and MES sodium can be mixed to attain the desired pH. Standard mixing tables using stock solutions to prepare a buffer of a given pH have been published.   MES sodium salt Preparation Products And Raw materials Product Name: 4-Phenoxyphenol Synonyms: 4-Phenoxyphenol ,97%;4-PHENOXYPHENOL FOR SYNTHESIS;P-PHENOXYPHENOL;POP;JR-7139, 4-Phenoxyphenol, 97%;4-phenoxy-pheno;Phenol, 4-phenoxy-;Phenol, p-phenoxy- CAS: 831-82-3 MF: C12H10O2 MW: 186.21 EINECS: 212-611-1 Product Categories: Building Blocks;C9 to C20+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Phenols;Aromatic Phenols;Phenoles and thiophenoles;831-82-3 Mol File: 831-82-3.mol   4-Phenoxyphenol Chemical Properties Melting point  80-84 °C (lit.) Boiling point  177-180°C (11 mmHg) density  1.1032 (rough estimate) refractive index  1.6010 (estimate) Fp  177-180°C/9mm storage temp.  Inert atmosphere,Room Temperature solubility  toluene: 0.1 g/mL, clear pka 10.07±0.13(Predicted) form  Solid color  colorless to light brown Water Solubility  insoluble BRN  2047182 Stability: Stable. Combustible. Incompatible with strong oxidizing agents. InChIKey ZSBDGXGICLIJGD-UHFFFAOYSA-N CAS DataBase Reference 831-82-3(CAS DataBase Reference) NIST Chemistry Reference 4-Phenoxyphenol(831-82-3) EPA Substance Registry System p-Phenoxyphenol (831-82-3)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-36-37/39 WGK Germany  3 Hazard Note  Irritant TSCA  Yes HS Code  29095090 MSDS Information Provider Language Hydroquinone monophenyl ether English ACROS English SigmaAldrich English ALFA English   4-Phenoxyphenol Usage And Synthesis Chemical Properties beige crystalline powder Uses 4-Phenoxyphenol is a porous organic material with dumbbell channels that appear throughout its structure. These channels can also host solvent molecules during crystal growth. 4-Phenoxyphenol is also part of a group of phenolic compounds that have potential apoptotic activity, which can be used in the development of new treatments for cancer therapy.   4-Phenoxyphenol Preparation Products And Raw materials Raw materials Dimethyl sulfoxide-->Bromobenzene-->Hydroquinone-->Potassium hydroxide solution-->Agitator,magnetic force driving-->Phenol, 4-phenoxy-, acetate-->4-PHENOXYPHENYLBORONIC ACID-->1,3-DIPHENOXYBENZENE-->4-Chlorodiphenyl ether-->1-METHOXY-4-PHENOXY-BENZENE Preparation Products 1,4-Diphenoxybenzene-->1-(4-Phenoxyphenoxy)-2-propanol Product Name: CALCIUM CITRATE MALATE Synonyms: 2-Hydroxy-1,2,3-propanetricarboxylic acid calcium salt mixt. with hydroxybutanedioic acid calcium salt;Citric acid malic acid calcium;Fruit acid calcium;Calcium Citrate Malate Fine Granular;142606-53-9 CALCIUM CITRATE MALATE CAS: 142606-53-9 MF: C16H14Ca4O19 MW: 0 EINECS:   Product Categories:   Mol File: 142606-53-9.mol   CALCIUM CITRATE MALATE Chemical Properties   Safety Information HS Code  2918195000 MSDS Information   CALCIUM CITRATE MALATE Usage And Synthesis Uses Calcium Citrate Malate, is the calcium salt of citric acid and malic acid with variable composition. It is water soluble and when dissolved, it releases calcium ions and a calcium-citrate complex into intestinal cells.   CALCIUM CITRATE MALATE Preparation Products And Raw materials

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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