China Largest Manuf...

China Largest Manufacturer factory sales 4-Hydroxyindole CAS 2380-94-1
China Largest Manufacturer factory sales 4-Hydroxyindole CAS 2380-94-1
China Largest Manufacturer factory sales 4-Hydroxyindole CAS 2380-94-1
China Largest Manufacturer factory sales 4-Hydroxyindole CAS 2380-94-1
China Largest Manufacturer factory sales 4-Hydroxyindole CAS 2380-94-1

China Largest Manufacturer factory sales 4-Hydroxyindole CAS 2380-94-1

Min.Order / FOB Price:Get Latest Price

500 Kilogram

FOB Price:USD 1.0000 -2.0000

  • Min.Order :500 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

4-Hydroxyindole 4-Hydroxyindole 2380-94-1

Quick Details

  • Appearance:white powder
  • Application:Pharm chemicals industry
  • PackAge:25KG/Drum
  • ProductionCapacity:20|Metric Ton|Month
  • Storage:2-8°C
  • Transportation:By air /Sea/ coruier

Superiority:

                                PRODUCT DETAILS                           

4-Hydroxyindole Basic information
Uses
Product Name: 4-Hydroxyindole
Synonyms: 4-Hdroxyindole;4-Hydroxyindole in stock Factory;1H-INDOL-4-OL;1H-INDOLE-4-OL;4-HYDROXY-1H-INDOLE;4-INDOLOL;4-HYDROXYINDOLE;INDOL-4-OL
CAS: 2380-94-1
MF: C8H7NO
MW: 133.15
EINECS: 219-177-2
Product Categories: API;Chemical;Indole;Indoles;Indole Derivatives;Heterocycle-Indole series;blocks;IndolesOxindoles;Indoles and derivatives;pharmacetical;Simple Indoles;Chiral Compound;Pyrroles & Indoles;Heterocycles;Heterocycles series;Pyrroles & Indoles
Mol File: 2380-94-1.mol
4-Hydroxyindole Structure
 
4-Hydroxyindole Chemical Properties
Melting point  97-99 °C(lit.)
Boiling point  245.66°C (rough estimate)
density  1.1475 (rough estimate)
refractive index  1.5260 (estimate)
storage temp.  0-6°C
solubility  DMSO (Slightly), Methanol (Slightly)
pka 9.89±0.40(Predicted)
form  Solid
color  Dark Yellow to Green-Grey
Water Solubility  slightly soluble
Sensitive  Air Sensitive
BRN  114905
InChIKey NLMQHXUGJIAKTH-UHFFFAOYSA-N
CAS DataBase Reference 2380-94-1(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
Hazard Note  Irritant
HazardClass  IRRITANT, KEEP COLD
HS Code  29339900
MSDS Information
Provider Language
4-Indolol English
SigmaAldrich English
ACROS English
ALFA English
 
4-Hydroxyindole Usage And Synthesis
Uses

4-Hydroxyindole as simple indoles is the important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers.

Chemical Properties Off-White Cyrstalline Solid
Uses Pindolol (P468000) impurity.
Uses inhibitor of Amyloid-beta deposition
Uses 4-Hydroxyindole is a Pindolol (P468000) impurity, which is a mixed adrenergic blocker and serotonin 5HT1A-receptor antagonist.
Definition ChEBI: A member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 4.
General Description

Glucouridination of 4-hydroxyindole by human uridine 5′-diphospho-glucuronosyltransferase has been repotrted.

 
4-Hydroxyindole Preparation Products And Raw materials
Raw materials tert-Butanol-->Paraformaldehyde-->Resorcinol-->N,N-Dimethylacetamide-->Indole-->Ethyl bromopyruvate-->2,6-Dinitrotoluene
Preparation Products 4-HO-DET-->Pindolol-->4-(oxiranylmethoxy)-1H-indole-->N-BOC-4-HYDROXYINDOLE-->4-Methoxy-indoline-2,3-dione-->4-HYDROXY-1H-INDOLE-3-CARBALDEHYDE
 
 



                                                                       Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

Our Factories production lines

                                                   Our Factories R&D ability

                        Our Factories warehouse 

                

Details:

                                                       Product information

4-Hydroxyindole Basic information
Uses
Product Name: 4-Hydroxyindole
Synonyms: 4-Hdroxyindole;4-Hydroxyindole in stock Factory;1H-INDOL-4-OL;1H-INDOLE-4-OL;4-HYDROXY-1H-INDOLE;4-INDOLOL;4-HYDROXYINDOLE;INDOL-4-OL
CAS: 2380-94-1
MF: C8H7NO
MW: 133.15
EINECS: 219-177-2
Product Categories: API;Chemical;Indole;Indoles;Indole Derivatives;Heterocycle-Indole series;blocks;IndolesOxindoles;Indoles and derivatives;pharmacetical;Simple Indoles;Chiral Compound;Pyrroles & Indoles;Heterocycles;Heterocycles series;Pyrroles & Indoles
Mol File: 2380-94-1.mol
4-Hydroxyindole Structure
 
4-Hydroxyindole Chemical Properties
Melting point  97-99 °C(lit.)
Boiling point  245.66°C (rough estimate)
density  1.1475 (rough estimate)
refractive index  1.5260 (estimate)
storage temp.  0-6°C
solubility  DMSO (Slightly), Methanol (Slightly)
pka 9.89±0.40(Predicted)
form  Solid
color  Dark Yellow to Green-Grey
Water Solubility  slightly soluble
Sensitive  Air Sensitive
BRN  114905
InChIKey NLMQHXUGJIAKTH-UHFFFAOYSA-N
CAS DataBase Reference 2380-94-1(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
Hazard Note  Irritant
HazardClass  IRRITANT, KEEP COLD
HS Code  29339900
MSDS Information
Provider Language
4-Indolol English
SigmaAldrich English
ACROS English
ALFA English
 
4-Hydroxyindole Usage And Synthesis
Uses

4-Hydroxyindole as simple indoles is the important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers.

Chemical Properties Off-White Cyrstalline Solid
Uses Pindolol (P468000) impurity.
Uses inhibitor of Amyloid-beta deposition
Uses 4-Hydroxyindole is a Pindolol (P468000) impurity, which is a mixed adrenergic blocker and serotonin 5HT1A-receptor antagonist.
Definition ChEBI: A member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 4.
General Description

Glucouridination of 4-hydroxyindole by human uridine 5′-diphospho-glucuronosyltransferase has been repotrted.

 
4-Hydroxyindole Preparation Products And Raw materials
Raw materials tert-Butanol-->Paraformaldehyde-->Resorcinol-->N,N-Dimethylacetamide-->Indole-->Ethyl bromopyruvate-->2,6-Dinitrotoluene
Preparation Products 4-HO-DET-->Pindolol-->4-(oxiranylmethoxy)-1H-indole-->N-BOC-4-HYDROXYINDOLE-->4-Methoxy-indoline-2,3-dione-->4-HYDROXY-1H-INDOLE-3-CARBALDEHYDE

 

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