China Largest Manufacturer factory sales Acetylpyrazine/2-acetyl pyrazine CAS 22047-25-2

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Acetylpyrazine Basic information Description References Product Name: Acetylpyrazine Synonyms: ACETYLPYRAZINE;ACETYLPYRAZINE, 2-;2-ACETYLPYRAZINE;1-PYRAZIN-2-YLETHAN-1-ONE;1-PYRAZIN-2-YL-ETHANONE;METHYL PYRAZINYL KETONE;METHYL-2-PYRAZINYL KETONE;FEMA 3126 CAS: 22047-25-2 MF: C6H6N2O MW: 122.12 EINECS: 244-753-5 Product Categories: Building Blocks;Chemical Synthesis;Chloropyrazines, etc.;pyrazine Flavor;Sulfides flavors;Heterocyclic Building Blocks;ACETYLGROUP;Pharmaceutical Intermediates;Pyrazines;Pyrazine;Heterocyclic Compounds;Miscellaneous;Building Blocks;Heterocyclic Building Blocks Mol File: 22047-25-2.mol   Acetylpyrazine Chemical Properties Melting point  76-78 °C (lit.) Boiling point  78-79°C 8mm density  1.1075 FEMA  3126 | ACETYLPYRAZINE refractive index  1.5350 (estimate) Fp  78-79°C/8mm storage temp.  Keep in dark place,Sealed in dry,Room Temperature solubility  Chloroform (Slightly), Methanol (Slightly) pka 0.30±0.10(Predicted) form  Solid color  White to Off-White Odor popcorn-like odor JECFA Number 784 BRN  109630 InChIKey DBZAKQWXICEWNW-UHFFFAOYSA-N CAS DataBase Reference 22047-25-2(CAS DataBase Reference) NIST Chemistry Reference Acetylpyrazine(22047-25-2) EPA Substance Registry System Ethanone, 1-pyrazinyl- (22047-25-2)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-36-24/25 WGK Germany  2 Hazard Note  Irritant TSCA  T HazardClass  IRRITANT HS Code  29339900 MSDS Information Provider Language 2-Acetylpyrazine English ACROS English ALFA English   Acetylpyrazine Usage And Synthesis Description 2-acetylpyrazine is white to pale yellow crystalline powder with a nutty, popcorn, bread-crust odor. It is soluble in water and stable under ordinary conditions. It is used to manufacture many polycyclic compounds and used as useful structures in pharmaceuticals and perfumes. It is a component of the folates (vitamin B compounds) and of the isoalloxazine ring nucleus of flavins. Numerous pyrazine derivatives such as pyrazine polycyclic compounds, alkyl-, alicyclic-, and alkylaryl-substituted compounds, derivatives containing oxygenated functional groups and thio-functional groups in the side-chains are used in biological, drug, flavoring and perfumery industry. 2-acetylpyrazine is used as food additive, commonly used in chocolate and baked goods. References [1] # [2] # [3] //www.chemicalland21.com/specialtychem/perchem/2-ACETYLPYRAZINE.htm Chemical Properties LIGHT YELLOW TO YELLOW-BROWNISH POWDER Chemical Properties Acetylpyrazine has a nutty, popcorn, bread crust odor. It is one of the volatile aroma components in popcorn, wheat and rye crusts. Occurrence Reported found in guava fruit (Psidium guajava L.), wheaten bread, other types of breads, boiled and cooked beef, grilled/roasted uncured pork, pork liver, cocoa, coffee, black tea, roasted barley, roasted filbert (Corylus avellano), roasted peanut (Arachis hypogea), roasted almond (Prunus amygdalus), scallop, filberts, popcorn and sesame oil. Uses Acetylpyrazine has been used in synthesis of: 7-heteroaryl-pyrazolo[1,5-a]pyrimidine-3-carboxamides copper (II) complexes with di-imine ligands N(4) substituted thiosemicarbazones Definition ChEBI: 2-acetylpyrazine is a pyrazine that is substituted by an acetyl group at position 2. It has been identified as one of the volatile flavor constituents in popcorn, bread crust, vinegar, and potato snacks. It has a role as a flavouring agent. It is an aromatic ketone and a member of pyrazines. Application Acetylpyrazine has been widely used as an intermediate in the organic synthesis of various heterocyclic derivatives and in coupling reactions, alkylation reactions, and sensitizer ligands because of its good biological and reactive activities. For example, it is a significant reaction intermediate for producing drugs for treating malaria, epilepsy, and Parkinson's disease. Preparation synthesis of acetylpyrazine: By the ester condensation of EtO2 C-pyrazine; by dehydrating pyrazynamide with POCI3 and then reacting the resulting 2-cyano-pyrazine with methyl magnesium bromide. Aroma threshold values Detection at 62 ppb Taste threshold values Taste characteristics at 10 ppm: roasted, nutty, bready, yeasty with popcorn, corn chip nuance General Description 2-Acetylpyrazine has been identified as one of the volatile flavor constituents in popcorn, wheat and rye bread crust.   Acetylpyrazine Preparation Products And Raw materials Raw materials Ethyl acetate-->Diethyl ether-->Dichloromethane-->PETROLEUM ETHER-->Magnesium-->Trifluoroacetic acid-->Ammonium persulfate-->Pyruvic acid-->Silver nitrate-->Pyrazine

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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