[N-α-Triglycyl-8-lysine]-vasopressin 14636-12-5 99% purity
Terlipressin acetate Basic information
Product Name: Terlipressin acetate
Synonyms: [N-α-Triglycyl-8-lysine]-vasopressin;130: PN: WO2010033207 SEQID: 171 claiMed protein;1-Triglycyl-8-lysine Vasopressin;Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin;Nα-Glycyl-glycyl-glycyl-lysine-vasopressin;Nα-Glycylglycylglycyl-vasopressin;Nα-Gly-Gly-Gly-8-Lys-vasopressin;Terlipressin, Terlipressine, Terlipressina, Terlipressinum
CAS: 14636-12-5
MF: C52H74N16O15S2
MW: 1227.37
EINECS: 238-680-8
Product Categories:
Mol File: 14636-12-5.mol
Terlipressin acetate Chemical Properties
Melting point >170°C (dec.)
Boiling point 1824.0±65.0 °C(Predicted)
density 1.46±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 9.90±0.15(Predicted)
form Solid
color White
CAS DataBase Reference 14636-12-5(CAS DataBase Reference)
Chemical Properties N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin is White Solid
Uses N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin is used norepinephrine-resistant septic shock and hepatorenal syndrome. N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin is also used in the treatment of acute variceal bleeding.
Clinical Use Treatment of bleeding oesophageal varices
Drug interactions Potentially hazardous interactions with other drugs
None known
Metabolism Terlipressin is metabolised by tissue peptidases resulting in the slow release of lypressin. Terlipressin is almost completely metabolised in the kidneys and liver, with less than 1% of terlipressin and less than 0.1% of lypressin excreted in the urine.
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