China Manufacturer factory sales 2-Acetylthiazole CAS 24295-03-2

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2-Acetylthiazole Basic information Description References Product Name: 2-Acetylthiazole Synonyms: THIAZOLE-2-ACETYL;1-(1,3-Thiazol-2-yl)ethanone;1-(2-thiazolyl)-ethanon;2-Acetylthiazol;2-Thiazolylmethylketone;Acetylthiazole;Ketone, methyl 2-thiazolyl;1-(2-thiazolyl)-ethanone CAS: 24295-03-2 MF: C5H5NOS MW: 127.16 EINECS: 246-134-5 Product Categories: A-B;Alphabetical Listings;thiazole Flavor;Flavors and Fragrances;Building Blocks;Heterocyclic Building Blocks;ACETYLGROUP;Sulphur Derivatives;Thiazoles Mol File: 24295-03-2.mol   2-Acetylthiazole Chemical Properties Melting point  65.5°C Boiling point  89-91 °C/12 mmHg (lit.) density  1.227 g/mL at 25 °C (lit.) FEMA  3328 | 2-ACETYLTHIAZOLE refractive index  n20/D 1.548(lit.) Fp  173 °F storage temp.  Inert atmosphere,Room Temperature pka 0.05±0.10(Predicted) form  Powder or Crystals color  White to slightly yellow Specific Gravity 1.23 Sensitive  Stench JECFA Number 1041 BRN  109803 CAS DataBase Reference 24295-03-2(CAS DataBase Reference) NIST Chemistry Reference 2-Acetylthiazole(24295-03-2) EPA Substance Registry System Ethanone, 1-(2-thiazolyl)- (24295-03-2)   Safety Information Hazard Codes  Xn,Xi Risk Statements  22-36-43-36/37/38 Safety Statements  26-36/37-24/25-36 RIDADR  3334 WGK Germany  3 F  13 Hazard Note  Irritant/Stench TSCA  T HazardClass  STENCH HS Code  29341000 MSDS Information Provider Language 2-Acetylthiazole English SigmaAldrich English ACROS English ALFA English   2-Acetylthiazole Usage And Synthesis Description 2-Acetylthiazole is a colorless to pale yellow liquid which has hazelnuts, roasted meat, caramel, corn, and butter flavors. It is naturally found in raw asparagus, cooked asparagus, kohlrabi, cooked or boiled potatoes, turkey (roasted), raw chicken, boiled and cooked beef, grilled and roasted beef, pork liver, beer, Finnish whiskey, heated beans, other varieties of mushroom, rice bran, maize, and other natural sources. It is used in foods as antioxidant, as appearance control agent, and as flavoring ingredient. References [1] George A. Burdock (1996) Encyclopedia of Food and Color Additives, Volume 1 Chemical Properties white to light yellow crystal powde Chemical Properties A colorless liquid with green onion, herbal, grassy odor. It is used as flavor enhancer and flavoring agent Occurrence Reported found in raw asparagus, cooked asparagus, kohlrabi, cooked or boiled potatoes, turkey (roasted), raw chicken, boiled and cooked beef, grilled and roasted beef, pork liver, beer, Finnish whiskey, heated beans, other varieties of mushroom, rice bran, and maize Uses 2-Acetylthiazole can be used as a flavoring agent in food industries. It may be used as a food additive in the preparation of ′fragrant′ rice. Uses 2-Acetylthiazole was used in the preparation of triazolothiazoles, chiral alcohols and in aldol condensation reactions. Preparation By oxidation of the corresponding carbinol using dichromate Aroma threshold values Detection at 4 ppb Taste threshold values Taste characteristics at 30 ppm: corn chip with slightly musty background Synthesis Reference(s) The Journal of Organic Chemistry, 53, p. 1748, 1988 DOI: 10.1021/jo00243a029 General Description 2-Acetylthiazole is a volatile flavoring substance generally formed by the Maillard reaction between an amino acid and carbonyl compounds. It is reported to occur in canned sweet corn products, cooked pine mushroom, cooked asparagus and roasted beef. Purification Methods Check NMR spectrum; if it is not too bad, distil it through an efficient column in a vacuum. The oxime sublimes at 140-145o, m 159o, and when crystallised from H2O has m 163-165.5o. [Erlenmeyer et al. Helv Chim Acta 31 1142 1948, Waisvisz et al. J Am Chem Soc 79 4524 1957, Menasseé et al. Helv Chim Acta 40 554 1957, Beilstein 27 IV 2617.]   2-Acetylthiazole Preparation Products And Raw materials Raw materials Ethyl acetate-->Diethyl ether-->Dichromate, Ion chromatography standard solution, Specpure, Cr2O7ˉ2 1000μg/ml-->2-Thiazolemethanol, alpha-methyl- (7CI,9CI) Preparation Products 1,2,5,6-Tetrathiocane-->2,5-Dihydrothiophene-->5-Chlorothiazole-2-ethanone

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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