China Largest Manufacturer factory Supply 5-Bromopyrimidine CAS 4595-59-9

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5-Bromopyrimidine Basic information Product Name: 5-Bromopyrimidine Synonyms: 5-bromo-pyrimidin;PYRIMIDINE, 2-BROMO-;PYRIMIDINE, 5-BROMO-;5-BROMOPYRIMIDINE;5-Bromopyrimidine,98%;Pyrimidine,5-bromo-(6CI,7CI,8CI,9CI);5-BROMOISATINIC ANHYDRIDE;5-BROMOPYRIMIDINE, 99% MIN CAS: 4595-59-9 MF: C4H3BrN2 MW: 158.98 EINECS: 224-992-1 Product Categories: Halides;Pyrazines, Pyrimidines & Pyridazines;Aromatics Compounds;Aromatics;Heterocycles;Pyrazines, Pyrimidines & Pyridazines;HALIDE;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks;Pyrimidine;Heterocycle-Pyrimidine series;Pyridines, Pyrimidines, Purines and Pteredines Mol File: 4595-59-9.mol   5-Bromopyrimidine Chemical Properties Melting point  67-73 °C (lit.) Boiling point  168°C(lit.) density  1.6448 (rough estimate) refractive index  1.5260 (estimate) storage temp.  Sealed in dry,Room Temperature solubility  Soluble in chloroform. form  Crystalline Powder or Chunks pka 1.40±0.10(Predicted) color  Yellow to beige-brown BRN  107326 CAS DataBase Reference 4595-59-9(CAS DataBase Reference) NIST Chemistry Reference Pyrimidine, 5-bromo-(4595-59-9) EPA Substance Registry System Pyrimidine, 5-bromo- (4595-59-9)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38-36/38 Safety Statements  26-36-37/39 WGK Germany  3 Hazard Note  Irritant TSCA  T HazardClass  IRRITANT, KEEP COLD HS Code  29335990 MSDS Information Provider Language 5-Bromopyrimidine English SigmaAldrich English ACROS English ALFA English   5-Bromopyrimidine Usage And Synthesis Chemical Properties yellow solid crystalline, insoluble in water, soluble in organic solvents such as benzene and toluene. Uses 5-Bromopyrimidine was used in the synthesis of N-heteroaryl substituted 9-arylcarbazolyl derivatives via palladium-catalyzed aerobic and ligand-free Suzuki reaction, (5-(phenylethynyl)pyrimidine) via microwave assisted organic synthesis (MAOS) Sonogashira protocol. Uses 5-Bromopyrimidine was used in the synthesis of: N-heteroaryl substituted 9-arylcarbazolyl derivatives via palladium-catalyzed aerobic and ligand-free Suzuki reaction (5-(phenylethynyl)pyrimidine) via microwave assisted organic synthesis (MAOS) Sonogashira protocol Intermediate for the synthesis of plant growth regulator flurprimidol Application 5-Bromopyrimidine is a compound useful in organic synthesis. Preparation 5-Bromopyrimidine is prepared by reacting dibromodifuranone with formamide in the presence of B2O2 catalyst at 180-185°C to obtain the product. General Description Rapid nucleophilic displacement reactions of 5-bromopyrimidine with nucleophiles under microwave irradiation has been studied. 5-Bromopyrimidine undergoes direct metallation with lithuium diisopropylamide to yield 4-lithio-5-bromopyrimidine.   5-Bromopyrimidine Preparation Products And Raw materials Raw materials 2,3-Dihydrofuran Preparation Products Pyrimidine-5-carboxaldehyde-->5-HYDROXYPYRIMIDINE-->5-Hydroxypyrimidine-->5-Pyrimidinecarboxylic acid-->5-Pyrimidinylboronic acid-->ETHYL 5-PYRIMIDINECARBOXYLATE 98-->3-PYRIMIDIN-5-YL-BENZOIC ACID-->METHYL PYRIMIDINE-5-CARBOXYLATE-->Pyrimidine, 5-bromo-4-methyl- (7CI,8CI,9CI)-->5-CYANOPYRIMIDINE-->Fenarimol

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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