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China Largest Manufacturer factory Supply Nuciferin CAS 475-83-2
China Largest Manufacturer factory Supply Nuciferin CAS 475-83-2
China Largest Manufacturer factory Supply Nuciferin CAS 475-83-2
China Largest Manufacturer factory Supply Nuciferin CAS 475-83-2
China Largest Manufacturer factory Supply Nuciferin CAS 475-83-2

China Largest Manufacturer factory Supply Nuciferin CAS 475-83-2

Min.Order / FOB Price:Get Latest Price

500 Kilogram

FOB Price:USD 1.0000 -2.0000
  • Min.Order :500 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Nuciferin Nuciferin 475-83-2

Quick Details

  • Appearance:white powder
  • Application:Pharm chemicals industry
  • PackAge:25KG/Drum
  • ProductionCapacity:20|Metric Ton|Month
  • Storage:2-8°C
  • Transportation:By air /Sea/ coruier

Superiority:

                                PRODUCT DETAILS       

NUCIFERINE Basic information Uses Product Name: NUCIFERINE Synonyms: (-)-nucipherine;(r)-1,2-dimethoxyaporphine;1,2-dimethoxy-6a-beta-aporphin;6a;4H-Dibenzo[de,g]quinoline,5,6,6a,7-tetrahydro-1,2-diMethoxy-6-Methyl-, (6aR)-;Nuciferine 1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline;satis indigotica fort Extract;Lotus Leaf Extract Nuciferin CAS: 475-83-2 MF: C19H21NO2 MW: 295.38 EINECS:  Product Categories: standardized herbal extract;chemical reagent;Miscellaneous Natural Products;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM). Mol File: 475-83-2.mol  NUCIFERINE Chemical Properties Melting point  165.5°C Boiling point  437.06°C (rough estimate) density  1.1156 (rough estimate) refractive index  1.5000 (estimate) storage temp.  2-8°C form  powder pka 7.87±0.20(Predicted) color  white to beige optical activity [α]/D -145 to -165°, c = 0.5 in ethanol Safety Information Safety Statements  24/25 RIDADR  UN 1544PSN1 6.1 / PGIII HS Code  29389090 Toxicity LD50 orl-rat: 280 mg/kg AIPTAK 197,261,72 MSDS Information NUCIFERINE Usage And Synthesis Uses The lotus leaf alkaloid has the effect of weight loss and lipid reduction, and can be used for content determination/identification/pharmacological experiments. Description Nuciferine is an aporphine alkaloid from Nelumbo lutea, the ba~e yields colourless crystals when crystallized from EtOH. It is laevorotatory, the following specific rotations having been recorded; [α] 22D- 157.5° and - 215°. The ultraviolet spectrum has three absorption maxima at 230, 272 and 310 mp. Two methoxyl groups and one methylimino group are present and the alkaloid may be characterized as the hydrochloride, m.p. 241°C (in vacuo) and the methiodide, m.p. 177-8°C. The optically inactive base has been synthesized and has m.p. 136-7°C, giving a hydrochloride in the form of small colourless prisms from H20, m.p. 258°C (dec.). Safety Profile Poison by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx. References Gulland, Haworth., J. Chern. Soc., 590 (1928) Yunusov, Konovalova, Orekhov., Bull. Soc. Chim. Fr., 70 (1940) Arthur, Cheung., J. Chern. Soc., 2306 (1959) Kupchan et al., Tetrahedron, 19, 227 (1963) NUCIFERINE Preparation Products And Raw materials
 



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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                       Product information

NUCIFERINE Basic information Uses Product Name: NUCIFERINE Synonyms: (-)-nucipherine;(r)-1,2-dimethoxyaporphine;1,2-dimethoxy-6a-beta-aporphin;6a;4H-Dibenzo[de,g]quinoline,5,6,6a,7-tetrahydro-1,2-diMethoxy-6-Methyl-, (6aR)-;Nuciferine 1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline;satis indigotica fort Extract;Lotus Leaf Extract Nuciferin CAS: 475-83-2 MF: C19H21NO2 MW: 295.38 EINECS:  Product Categories: standardized herbal extract;chemical reagent;Miscellaneous Natural Products;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM). Mol File: 475-83-2.mol  NUCIFERINE Chemical Properties Melting point  165.5°C Boiling point  437.06°C (rough estimate) density  1.1156 (rough estimate) refractive index  1.5000 (estimate) storage temp.  2-8°C form  powder pka 7.87±0.20(Predicted) color  white to beige optical activity [α]/D -145 to -165°, c = 0.5 in ethanol Safety Information Safety Statements  24/25 RIDADR  UN 1544PSN1 6.1 / PGIII HS Code  29389090 Toxicity LD50 orl-rat: 280 mg/kg AIPTAK 197,261,72 MSDS Information NUCIFERINE Usage And Synthesis Uses The lotus leaf alkaloid has the effect of weight loss and lipid reduction, and can be used for content determination/identification/pharmacological experiments. Description Nuciferine is an aporphine alkaloid from Nelumbo lutea, the ba~e yields colourless crystals when crystallized from EtOH. It is laevorotatory, the following specific rotations having been recorded; [α] 22D- 157.5° and - 215°. The ultraviolet spectrum has three absorption maxima at 230, 272 and 310 mp. Two methoxyl groups and one methylimino group are present and the alkaloid may be characterized as the hydrochloride, m.p. 241°C (in vacuo) and the methiodide, m.p. 177-8°C. The optically inactive base has been synthesized and has m.p. 136-7°C, giving a hydrochloride in the form of small colourless prisms from H20, m.p. 258°C (dec.). Safety Profile Poison by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx. References Gulland, Haworth., J. Chern. Soc., 590 (1928) Yunusov, Konovalova, Orekhov., Bull. Soc. Chim. Fr., 70 (1940) Arthur, Cheung., J. Chern. Soc., 2306 (1959) Kupchan et al., Tetrahedron, 19, 227 (1963) NUCIFERINE Preparation Products And Raw materials
 

 

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