China Largest Manufacturer factory Supply Glycolic acid CAS 79-14-1

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Glycolic acid Basic information Description References Product Name: Glycolic acid Synonyms: Acetic acid, 2-hydroxy-;AKOS BBS-00004277;2-HYDROXYACETIC ACID;GLYCOLIC ACID, HIGH PURITY, 70 WT.% SOLU TION IN WATER;GLYCOLIC ACID REAGENTPLUS(TM) 99%;GLYCOLIC ACID SOLUTION, ~55% IN WATER;GLYCOLIC ACID, TECH., 70 WT. % SOLUTION IN WATER;GLYCOLIC ACID SIGMAULTRA CAS: 79-14-1 MF: C2H4O3 MW: 76.05 EINECS: 201-180-5 Product Categories: Oil Industry;Halogenated Heterocycles ,Carbazoles ,Indazoles;Roxatidine Acetate;omega-Hydroxycarboxylic Acids;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Organic acids;Pharmaceutical Intermediates;Hydroxycarboxylic Acids (for High-Performance Polymer Research);Aliphatics;Building Blocks;C1 to C5;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Functional Materials;Reagent for High-Performance Polymer Research;Cosmetic Ingredients & Chemicals;Organic Building Blocks;Aliphatic Compounds;Allium cepa (Onion);Nutrition Research;Phytochemicals by Chemical Classification;Phytochemicals by Plant (Food/Spice/Herb) Mol File: 79-14-1.mol   Glycolic acid Chemical Properties Melting point  75-80 °C (lit.) Boiling point  112 °C density  1.25 g/mL at 25 °C vapor pressure  10.8 hPa (80 °C) refractive index  n20/D 1.424 Fp  112°C storage temp.  Store below +30°C. solubility  H2O: 0.1 g/mL, clear pka 3.83(at 25℃) form  Solution color  White to off-white PH 2 (50g/l, H2O, 20℃) Water Solubility  SOLUBLE Sensitive  Hygroscopic Merck  14,4498 BRN  1209322 Stability: Stable. Incompatible with bases, oxidizing agents and reducing agents. InChIKey AEMRFAOFKBGASW-UHFFFAOYSA-N CAS DataBase Reference 79-14-1(CAS DataBase Reference) NIST Chemistry Reference Acetic acid, hydroxy-(79-14-1) EPA Substance Registry System Glycolic acid (79-14-1)   Safety Information Hazard Codes  C Risk Statements  34-22-20 Safety Statements  26-36/37/39-45-23 RIDADR  UN 3265 8/PG 3 WGK Germany  1 RTECS  MC5250000 TSCA  Yes HS Code  2918 19 98 HazardClass  8 PackingGroup  II Hazardous Substances Data 79-14-1(Hazardous Substances Data) Toxicity LD50 orally in rats: 1.95 g/kg, H. F. Smyth et al., J. Ind. Hyg. Toxicol. 23, 259 (1941) MSDS Information Provider Language ACROS English SigmaAldrich English ALFA English   Glycolic acid Usage And Synthesis Description Glycolic acid is the smallest alpha-hydroxy acid (AHA). It is mainly supplemented to various skin-care products to improve the skin’s appearance and texture. It can also reduce wrinkles, acne scarring, and hyperpigmentation. In textile industry, it can be used as a dyeing and tanning agent. It can also be used as a flavoring agent in food processing, and as a skin care agent in the pharmaceutical industry. It can also be added into emulsion polymers, solvents and ink additives to improve flow properties and impart gloss. Moreover, it is a useful intermediate for organic synthesis including oxidative-reduction, esterification and long chain polymerization. References Bhatia, A. C., and F. Jimenez. "Rapid treatment of mild acne with a novel skin care system containing 1% salicylic acid, 10% buffered glycolic acid, and botanical ingredients." Journal of Drugs in Dermatology Jdd13.6(2014):678-83. # # Chemical Properties Glycolic acid, CH20HCOOH, also known as hydroxyacetic acid, is composed of colorless deliquescent leaflets that decompose at approximately 78° C (172 OF). It is soluble in water,alcohol,and ether.Glycolic acid is used in dyeing, tanning, electropolishing,and in foodstuffs. It is produced by oxidizing glycol with dilute nitric acid. Uses In the processing of textiles, leather, and metals; in pH control, and wherever a cheap organic acid is needed, e.g. in the manufacture of adhesives, in copper brightening, decontamination cleaning, dyeing, electroplating, in pickling, cleaning and chemical milling of metals. Uses glycolic acid (hydroxyacetic acid) reduces corenocyte cohesion and corneum layer thickening where an excess buildup of dead skin cells can be associated with many common skin problems, such as acne, dry and severely dry skin, and wrinkles. glycolic acid acts by dissolving the internal cellular cement responsible for abnormal keratinization, facilitating the sloughing of dead skin cells. It also improves skin hydration by enhancing moisture uptake as well as increasing the skin’s ability to bind water. This occurs in the cellular cement through an activation of glycolic acid and the skin’s own hyaluronic acid content. Hyaluronic acid is known to retain an impressive amount of moisture and this capacity is enhanced by glycolic acid. As a result, the skin’s own ability to raise its moisture content is increased. glycolic acid is the simplest alpha hydroxyacid (AHA). It is also the AHA that scientists and formulators believe has greater penetration potential largely due to its smaller molecular weight. It is mildly irritating to the skin and mucous membranes if the formulation contains a high glycolic acid concentration and/ or a low pH. glycolic acid proves beneficial for acne-prone skin as it helps keep pores clear of excess keratinocytes. It is also used for diminishing the signs of age spots, as well as actinic keratosis. However, glycolic acid is most popularly employed in anti-aging cosmetics because of its hydrating, moisturizing, and skin-normalizing abilities, leading to a reduction in the appearance of fine lines and wrinkles. Regardless of the G skin type, glycolic acid use is associated with softer, smoother, healthier, and younger looking skin. glycolic acid is naturally found in sugarcane but synthetic versions are most often used in cosmetic formulations. Definition ChEBI: A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated. Purification Methods Crystallise it from diethyl ether. [Beilstein 3 IV 571.]   Glycolic acid Preparation Products And Raw materials Raw materials Sodium hydroxide-->CARBON DIOXIDE-->Sodium cyanide-->HYDROGEN CYANIDE-->Methyl glycolate-->TARTRONIC ACID-->glyceric acid-->Gluconic acid-->D-Glucuronic acid-->D(+)-Xylose Preparation Products Chloroacetic acid-->Ethylenediaminetetraacetic acid-->Acemetacin-->Mefenacet-->1H-BENZIMIDAZOLE-2-CARBONYL CHLORIDE HYDROCHLORIDE-->PGA and its copolymer-->Methyl glycolate-->Indole-3-acetic acid-->Acetoxyacetyl chloride-->2-Benzimidazolecarboxylic acid-->2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate-->1,3-Dioxolane-4-methanol-->1H-Benzimidazole-2-methanol-->2,2-Dinitroethanol

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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