China Largest Manufacturer factory sales SODIUM ACETATE TRIHYDRATE CAS 6131-90-4

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Sodium acetate trihydrate Basic information Product Name: Sodium acetate trihydrate Synonyms: Acetic acid, sodium salt trihydrate, for analysis;Acetic acid, sodium salt trihydrate, for analysis ACS;Acetic acid sodium trihydrate;Acetic acid sodium·trihydrate;Sodium Acetate Trihydrate, Acs-100.5%;Acetic acid, sodium salt trihydrate, for analysis ACS, 99+%;SodiuM Acetate (AS);SodiuM Acetate, Trihydrate, HPLC Grade CAS: 6131-90-4 MF: C2H9NaO5 MW: 136.08 EINECS: 612-115-9 Product Categories: mordant dyes;Food additive;API;printing and dyeing;Organic chemistry;Food Additives;INORGANIC & ORGANIC CHEMICALS;Inorganic Chemicals Mol File: 6131-90-4.mol   Sodium acetate trihydrate Chemical Properties Melting point  58 °C Boiling point  >400°C density  1,45 g/cm3 Fp  >250°C storage temp.  Store at +5°C to +30°C. solubility  H2O: 3 M at 20 °C, clear, colorless form  Solid color  White tranparent Odor Slight acetic acid PH Range 8.5 - 10 at 408 g/l at 25 °C PH 7.5-9.0 (25℃, 50mg/mL in H2O) pka 4.76 (acetic acid)(at 25℃) Water Solubility  762 g/L (20 ºC) λmax λ: 260 nm Amax: ≤0.01 λ: 280 nm Amax: ≤0.01 Merck  14,8571 BRN  3732037 Stability: Stable. Incompatible with strong oxidizing agents, halogens. InChIKey AYRVGWHSXIMRAB-UHFFFAOYSA-M CAS DataBase Reference 6131-90-4(CAS DataBase Reference) NIST Chemistry Reference Sodium acetate trihydrate(6131-90-4) EPA Substance Registry System Acetic acid, sodium salt, trihydrate (6131-90-4)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  24/25-36-26 WGK Germany  1 RTECS  AJ4580000 Autoignition Temperature 607 °C TSCA  Yes HS Code  29152200 Toxicity LD50 orally in Rabbit: 3530 mg/kg LD50 dermal Rabbit > 10000 mg/kg MSDS Information Provider Language Acetic acid sodium salt trihydrate English SigmaAldrich English ACROS English ALFA English   Sodium acetate trihydrate Usage And Synthesis Description Sodium acetate trihydrate is the trihydrate sodium salt oaf acetic acid. In the food industry, sodium acetate is used as an acidity regulator, emulsifier, and preservative. It can give potato chips a salt and vinegar flavor. In pharmaceutical industry, it is used for replenishing lost electrolytes, as a diuretic, and in reusable heating pads and hand warmers. Sodium acetate trihydrate can be used to neutralize the industrial mineral acids discharge. In the textile and synthetic rubber production, it is used to neutralize sulfuric acids, facilitate aniline dye take up, and protect aniline day. In the leather industry, it is used as a buffering agent for leather tanning. Furthermore, sodium acetate trihydrate is used as buffers in the production of cosmetics and petroleum products and in electroplating industry. Chemical Properties white to colourless crystals or powder Chemical Properties Anhydrous salt is a colorless crystalline solid; density 1.528 g/cm3; melts at 324°C; very soluble in water; moderately soluble in ethanol. The colorless crystalline trihydrate has a density 1.45 g/cm3; decomposes at 58°C; is very soluble in water; pH of 0.1M aqueous solution is 8.9; moderately soluble in ethanol, 5.3 g/100mL. Chemical Properties Sodium acetate occurs as colorless, transparent crystals or a granular crystalline powder with a slight acetic acid odor. Uses Used as buffers. Uses Sodium acetate is a mordant in dyeing. Other applications are in photography, as an additive to food, in purification of glucose, in preservation of meat, in tanning, and as a dehydrating agent. In analytical chemistry it is used to prepare buffer solution. Uses In photography, analytical laboratory as buffer and in pharmaceutical.Sodium acetate trihydrate is used in various applications. It is used as a buffer of a pH range in between to 4.0 to 6.0. It is also used in the purification and precipitation of nucleic acids and in protein crystallization. It is used as a mordant dyeing, as a pickling agent in chrome tanning, as a neutralizer in waste streams containing sulfuric acid, in the textile industry and as a photoresist while using aniline dyes. It plays an important role to retard vulcanization of chloroprene in synthetic rubber production. It is a precursor to prepare ester from alkyl halide. Preparation Sodium acetate is prepared by reacting sodium hydroxide or sodium carbonate with acetic acid in aqueous solution. The solution is evaporated to obtain hydrated crystals of sodium acetate. NaOH + CH3COOH → CH3COONa + H2O Na2CO3 + CH3COOH → 2CH3COONa + CO2 + H2O Production Methods Sodium acetate is prepared by neutralization of acetic acid with sodium carbonate. General Description Sodium acetate trihydrate can be obtained from the crystallization of sodium acetate in water. On heating at 75°C, it melts, while on heating above 120°C it loses water of crystallization and gets converted into anhydrous form. The hyperfine proton and 13C splittings have been evaluated by recording ESR spectra of its irradiated single crystals. ESR studies suggested the existence of trapped methyl radicals. Its crystals are monoclinic and its crystal structure has been investigated by photographic methods. Unit cell parameters were evaluated. Pharmaceutical Applications Sodium acetate is used as part of a buffer system when combined with acetic acid in various intramuscular, intravenous, topical, ophthalmic, nasal, oral, otic, and subcutaneous formulations. It may be used to reduce the bitterness of oral pharmaceuticals. It can be used to enhance the antimicrobial properties of formulations; it has been shown to inhibit the growth of S. aureus and E. coli, but not C. albicans in protein hydrolysate solutions. It is widely used in the food industry as a preservative. Sodium acetate has also been used therapeutically for the treatment of metabolic acidosis in premature infants, and in hemodialysis solutions. Biochem/physiol Actions Sodium acetate trihydrate (SAT) is a phase change material (PCM) that can be easily combined with the preparation of domestic hot water, space heating, solar heating, and radiant floor heating systems. The hydrated salt of SAT possesses high latent heat density and thus can be used for low-temperature heat storage. Safety Sodium acetate is widely used in cosmetics, foods, and pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material. A short-term feeding study in chickens with a diet supplemented with 5.44% sodium acetate showed reduced growth rates that were attributed to the sodium content.(9) Sodium acetate is poisonous if injected intravenously, is moderately toxic by ingestion, and is an irritant to the skin and eyes. LD50 (rat, oral): 3.53 g/kg LD50 (mouse, IV): 0.38 g/kg LD50 (mouse, SC): 8.0 g/kg storage Sodium acetate should be stored in airtight containers. Incompatibilities Sodium acetate reacts with acidic and basic components. It will react violently with fluorine, potassium nitrate, and diketene. Regulatory Status GRAS listed. Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (injections, nasal, otic, ophthalmic, and oral preparations). References [1] //www.europlat.org [2] //www.rxlist.com/sodium-acetate-drug.htm [3] //cosmetics.specialchem.com [4] //cecri.csircentral.net/2710/1/036-96.pdf   Sodium acetate trihydrate Preparation Products And Raw materials Raw materials Sodium hydroxide-->Acetic acid-->Sodium carbonate-->Activated carbon Preparation Products 1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE-->ISOXANTHOPTERIN-->Gardenia blue pigment-->Pigment Red 13-->5-Ethyl-2-thiophenecarboxaldehyde-->2-Acetyl pyrrole-->5-[(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)METHYL]-2-FURALDEHYDE-->3-(2-FURYL)ISOXAZOL-5-AMINE-->5-METHYL-4-ISOXAZOLECARBONYL CHLORIDE-->2-AMINO-4-(4-CHLORO-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER-->6-AMINO-5-NITROSO-3-METHYLURACIL-->2,6-Dithiopurine-->Cefotaxime-->LEAD PHOSPHITE, DIBASIC-->3-Amino-5-phenylpyrazole-->Coumarin 30-->Pigment Red 175-->Cephalothin sodium-->Geranyl acetate-->6-HYDROXY-7-METHOXYCOUMARIN-->BISPYRAZOLONE-->VINYL STEARATE-->Pigment Red 32-->Sodium diacetate-->o-Anisic acid-->8-METHOXYCOUMARIN-->6-METHOXYCOUMARIN-->PALMITIC ACID VINYL ESTER-->3,3'-Dihydroxybenzidine-->C. I. Pigment Red 258-->Pigment Yellow 65-->softener IS-->D-alpha-Tocopheryl acetate-->ACID BLUE 92-->Pigment Yellow 83-->glyceryl ethercarboxylic acid salt-->4-Hydroxy-3-methoxystyrene-->Phenethyl acetate-->7-isopropyl-4-methyloxepan-2-one-->RHODINYL ACETATE

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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