China Largest Factory Manufacturer sales Leonurine Hydrochloride CAS 24697-74-3

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Leonurine hydrochloride Basic information Product Name: Leonurine hydrochloride Synonyms: Leonurine 4-Guanidino-1-butanol syringate;SCM-198;leonurine hydrochloride;4-Guanidino-1-butanol syringate;4-(diaminomethylideneamino)butyl 4-hydroxy-3,5-dimethoxy-benzoate hydrochloride;Leonurine;LEONURINE HCL;4-Hydroxy-3,5-dimethoxybenzoic acid 4-guanidinobutyl ester CAS: 24697-74-3 MF: C14H21N3O5 MW: 311.33 EINECS: 683-174-6 Product Categories: phytochemical;reference standards from Chinese medicinal herbs (TCM).;chemical reagent;pharmaceutical intermediate;standardized herbal extract Mol File: 24697-74-3.mol   Leonurine hydrochloride Chemical Properties Melting point  238 °C Boiling point  496.7±55.0 °C(Predicted) density  1.29±0.1 g/cm3(Predicted) storage temp.  Keep in dark place,Inert atmosphere,2-8°C solubility  DMSO: soluble2mg/mL, clear (warmed) pka 8.26±0.25(Predicted) form  powder color  white to beige Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. InChIKey WNGSUWLDMZFYNZ-UHFFFAOYSA-N   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-24/25 WGK Germany  3 HS Code  29399990 MSDS Information   Leonurine hydrochloride Usage And Synthesis Description An amorphous alkaloid, leonurine has been obtained from the leaves of Leonurus sibiricus L. and is characterized as the crystalline hydrochloride hydra te, m.p. 19l-4°C. Hydrolysis yields syringic acid and Q-hydroxybutylguanidine. The total synthesis of the alkaloid has been achieved, confirming the above structure. Uses Leonurine is a pseudoalkaloid that has been isolated from Leonotis leonurus. A natural product with antioxidant, anti-inflammatory and cardioprotective properties for the treatment of wild variety of conditions including stroke, cerebral thrombosis and cardiovascular diseases. Uses Leonurine Hydrochloride is an alkaloid plant extract used in the treatment of uterine disorders. Used in the modification of uterine contractions in rats. References Kubota, Nakajima., Nippon Yakubusugaku Zasshi., 163 (1930) Goto et al., Tetrahedron Lett., 545 (1962) Total synthesis: Kishi et al., Tetrahedron Lett., 637 (1968)   Leonurine hydrochloride Preparation Products And Raw materials

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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