China Largest Factory Manufacturer sales CHOLESTEROL ESTERASE CAS 9026-00-0

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CHOLESTEROL ESTERASE Basic information Product Name: CHOLESTEROL ESTERASE Synonyms: Cholesterol Esterase from hog pancreas, Sterol-ester acylhydrolase;Cholesterol Esterase from Pseudomonas fluorescens,Sterol-ester acylhydrolase;Cholesterol Esterase from bovine pancreas,Sterol-ester acylhydrolase;Cholesterol esterase froM pseudoMonas sp;Cholesterol Esterase from porcine pancreas,Cholesterol Esterase from hog pancreas, Sterol-ester acylhydrolase;Biocatalytics E3;Bucelipase alfa;CE (PP), Sterol esterase, sterol-ester acylhydrolase CAS: 9026-00-0 MF: NULL MW: 0 EINECS: 232-808-6 Product Categories: enzyme;Enzymes Mol File: Mol File   CHOLESTEROL ESTERASE Chemical Properties storage temp.  -20°C solubility  Dissolve 1mg/ml in 0.1M phosphate buffer, pH 6.0 to 7.0 form  powder color  white EPA Substance Registry System Esterase, cholesterol (9026-00-0)   Safety Information Safety Statements  22-24/25 WGK Germany  3 F  10-21 TSCA  Yes HS Code  35079090 MSDS Information Provider Language SigmaAldrich English   CHOLESTEROL ESTERASE Usage And Synthesis Chemical Properties Powder Uses Cholesterol Esterase is used for enzymatic determination of total cholesterol when coupled with cholesterol oxidize in clinical analysis. Cholesterol esterase (CE) is a reversible enzyme that can hydrolyze or synthesize fatty acid esters of cholesterol and other sterols. Uses Cholesterol Esterase from porcine pancreas has been used: in an in vitro simulated digestion model to improve the hydrolysis of carotenoid esters in the intestinal phase to analyze the bioavailability of phytosterol and cholesterol in the aqueous micellar phase of an in vitro simulated digestion model as a standard in enzyme activity assay Uses Cholesterol Esterase from bovine pancreas has been used: in γ-oryzanol-hydrolyzing activity in cholesterol esterase enzyme activity for quantification of cholesterol and cholesterol esters associated in tear film and lenses samples to test in vitro degradation of poly(fumaroyl bioxirane) maleate (PFM) polymer designed for bone tissue engineering General Description Cholesterol Esterase is a serine hydrolase released from the exocrine pancreas. It belongs to the α/β hydrolase family of enzymes. Biochem/physiol Actions Cholesterol esterase (CE) is a reversible enzyme that can hydrolyze or synthesize fatty acid esters of cholesterol and other sterols. Hydrolysis of water insoluble long chain fatty acid esters requires bile salt activation. Hydrolysis of water soluble esters of short chain fatty acids and lysophospholipids does not require activation by bile salts. It also hydrolyzes tri-, di-, and mono-acylglycerols, phospholipids, lysophospholipids, and ceramides. The enzyme may have multiple functions in lipid and lipoprotein metabolism, as well as in atherosclerosis. Its molecular mass is approximately 129 kDa and the optimum pH range is 7.0-9.0. The enzyme is activated by cholic acid, glycocholic acid, BSA, Mg2+ and 0.3% (v/v) X-100. Ag+, Hg2+ and ionic detergents inhibit the activity of the enzyme.   CHOLESTEROL ESTERASE Preparation Products And Raw materials

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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