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medroxyprogesterone 520-85-4 Medroxyprogesteronum
Quality:
1. order products, before delivery, according to customer needs, we will provide such as coa, msds, nuclear magnetic resonance (nmr), chiral product spinning, or customer specified demand quality indicators.
2. can be given sample and technical confirmation.
3. professional packaging, or packaging and transportation according to the needs of customers.
Service:
1. track the product freight service all the way.
2. to cooperate with the customs clearance.
3. optimize the production process according to the customer's needs.
4. joint research and development of products according to customer needs.
English name: medroxyprogesterone
CAS Number: 520-85-4
Molecular formula: C22H32O3
Molecular weight: 344.48800
Exact mass: 344.23500
PSA: 54.37000
LogP: 4.08440
Density: 1.13g/cm
Melting point: 220-223.5ºC
Boiling point: 488ºC at 760mmHg
Flash point: 263ºC
Refractive index: 1.538
pharmacological action
Medroxyprogesterone is a potent progestin without estrogenic activity. After oral administration or injection, on the basis of an appropriate amount of endogenous estrogen in the body, the proliferative endometrium can be transformed into the secretory endometrium to prepare for the implantation of fertilized eggs. Its progesterone activity is 20 to 30 times that of progesterone when injected subcutaneously, and 10 to 15 times that of progesterone when taken orally.
The main function is to promote the proliferation and secretion of the endometrium, complete the preparation for conception, and protect the safe growth of the fetus; it also has the functions of changing the menstrual cycle, enhancing the consistency of cervical mucus and inhibiting ovulation. Large doses of medroxyprogesterone have anti-tumor effects, and also significantly increase appetite and relieve pain in patients. Medroxyprogesterone has the effect of anti-estrogen, but it does not oppose the benign effect of estrogen on lipoprotein, and it has no obvious androgenic effect. It is the closest to natural progesterone. It can mainly increase the viscosity of cervical mucus. Large doses can inhibit pituitary gonadotropin and inhibit ovulation. It has a long-term anti-fertility effect. When medroxyprogesterone is used as an anti-tumor hormone, it has been proved through years of experiments and clinical studies that this type of preparation can have a dual effect, which is related to the dose.
Applicable symptoms
Erectile dysfunction and pulmonary hypertension.
Dosage
The recommended dose of this product is 10mg, which is taken before sexual activity and is not affected by food. If the effect of taking 10mg is not significant, you can take 20mg, at least 30 minutes before sex.
The maximum frequency of dosing is once a day.
Quality:
1. order products, before delivery, according to customer needs, we will provide such as coa, msds, nuclear magnetic resonance (nmr), chiral product spinning, or customer specified demand quality indicators.
2. can be given sample and technical confirmation.
3. professional packaging, or packaging and transportation according to the needs of customers.
Service:
1. track the product freight service all the way.
2. to cooperate with the customs clearance.
3. optimize the production process according to the customer's needs.
4. joint research and development of products according to customer needs.
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