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dexamethasone base Raw Material Dexamethasone Dexamethasone sodium phosphate
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Dexamethasone 50-02-2
Product Name : Dexamethasone
Dexamethasone
Cas No.: 50-02-2
MW: 392.46
MF: C22H29FO5
Description: white or white crystalline powder;odourless
Identification: positive
When melting point: 254 ℃ ~ 264 ℃, melting and decomposition
Than the curl: + 72 DHS ~ + 82 DHS
Absorption coefficient: 380 ~ 380
About material: maximum impurity 1.0% or less, impurities total 2.0% or less
Dry weight loss: 0.5% or less
On ignition residue: 0.2% or less
Content: in terms of avoiding C22H29FO5 should be 97.0% ~ 102.0%
Product categories: adrenocortical hormones API
Main description: mainly used for anti-inflammatory and anti-allergic, applicable to rheumatoid arthritis and other collagen diseases, etc
Storage: shading, sealing preservation
Product specifications: 1 kg/listen
Adrenocorticotropic hormone drugs, anti-inflammatory, anti-allergic and anti-drug more effective than prednisone, and promoting the removal of potassium sodium retention is very light, intramuscular or intravenous pituitary - adrenal strong inhibition:
1. Anti-inflammatory effects: Dexamethasone can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. Hormone suppression of inflammatory cells, including leukocytes and macrophages accumulation in sites of inflammation and inhibition of phagocytosis, lysosomal enzyme release and synthesis and release of inflammatory chemical mediators. Can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance.
2. Immunosuppressive effect: preventing or inhibiting cell-mediated immune response, delayed hypersensitivity reactions, reducing T lymphocytes, monocytes, eosinophils, reducing immunoglobulin binding to cell surface receptors and inhibition of the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response. Can reduce immune complexes through the basement membrane, and can reduce the concentration of ingredients complement and immunoglobulins.
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