Factory Price API 99% Cefamandole Nafate CAS 42540-40-9 Cemandil sodium salt

Superiority:

English name: Cemandil sodium salt

CAS number: 42540-40-9

Molecular formula: C19H17N6NaO6S2

Molecular weight: 512.49

EINECS Number: 255-877-4

Cefmandole sodium is a second-generation cephalosporin antibiotic with strong bactericidal effect. It has some advantages of the first and third-generation cephalosporins. The antibacterial activity of cefamandole sodium is only 1/10 to 1/5 of that of cefamandol, and cefamandole sodium is rapidly hydrolyzed into cefamandol when it enters the body, so the antibacterial effects of the two in vivo are basically the same. Cefmandole has a strong antibacterial effect on most gram-positive cocci, and its activity is similar to that of cefotaxime and cefazolin. Enterococcus and methicillin-resistant Staphylococcus aureus are resistant to this product. This product has a good effect on diphtheria bacillus and gram-positive anaerobic bacteria (anaerobic coccus and clostridium spp), and has a higher activity against Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae and Haemophilus influenzae. Cefotaxime and cefazolin are strong, and some Enterobacter aerogenes, indole-positive Proteus and Pruvidian are all sensitive to this product. Salmonella typhi, Shigella, Neisseria gonorrhoeae and Neisseria meningitidis are also very sensitive to this product, and have poor antibacterial effect on Bacteroides fragilis. Serratia, Alcaligenes, Acinetobacter and Pseudomonas aeruginosa are resistant to this product. Its mechanism of action is to combine with penicillin-binding proteins (PBPs) on the bacterial cell membrane, acylate transpeptidase, inhibit the synthesis of bacterial septum and cell wall, affect the cross-linking of cell wall mucopeptide components, and inhibit cell division and growth. The bacterial morphology grows and eventually dissolves and dies. The chemical name of cefamandole sodium is 7-D-(2-formyloxyphenylacetamide)-3-[(1-methyl-1H-tetrazol-5-yl)mercaptomethyl]-3-cephem- 4-Carboxylic acid sodium salt, suitable for lung infection, urinary tract infection, biliary tract infection, skin and soft tissue infection, bone and joint infection, sepsis, abdominal infection, etc. caused by sensitive bacteria.

For lung infections, urinary tract infections, biliary tract infections caused by Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella, Staphylococcus aureus, β-hemolytic Streptococcus, Proteus mirabilis, Escherichia coli, etc. , skin and soft tissue infections, bone and joint infections and sepsis, intra-abdominal infections.

Why choose KANAL:

1. quality
our products meet msds safe standard and we have iso and other certificate so you can get high quality products from our company.
2. price
we are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.
3.packing
we can do according to the customers' request.
4.transport
ems,dhl, tnt, ups ,fedex, by air, by sea
dhl express, fedex and ems for quantity less than 50kg, usually called as ddu service; 
sea shipping for quantity over 500kg; and air shipping is available for 50kg above;
for high value products, please select air shipping and dhl express for safe;
5.service
we offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.
we will try our best to satisfied you.
1. tailor-made for every customers. 
2. third-party test for the products you demand. 
3. test your counter-samples and produce them for you. 
4. best discount for old customers. 

1. We has 11 years' exporting experience in pharmaceutical ingredient products.

Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.