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Abarelix Abarelix CAS 183552-38-7 USP Abarelix GMP Producer
Abarelix is an antagonist of the releasing-hormone (Gn RH) receptor, and it was launched as an intramuscular injection for the palliative treatment of advanced symptomatic prostate cancer. Abarelix is a decapeptide, and it is prepared by a typical coupling cycle for peptide synthesis using Boc-amino acids and a methylbenzhydrylamine (MBHA) resin.
Name | Abarelix Acetate |
CAS No. | 183552-38-7 |
Molecular Formula | C72H95ClN14O14 |
Molecular Weight | 1416.06 |
Storage temp | Below-20°C |
Appearance | White powder |
Density | 1.287 g/cm3 |
Boiling Point | 1688.37 °C |
Flash Point | 974.891 °C |
Function:
Abarelix, an antineoplastic drug, is the first approved storable gonadotropin-releasing hormone antagonist formulation and the first new type of prostate cancer drug
Abarelix reduces testosterone production in the testis by directly inhibiting luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion. Due to the direct inhibition of LH secretion, the plasma testosterone concentration does not increase and then decrease. The results of the study showed that abarelix acetate has a high affinity for the LHRH receptor in the rat pituitary.
Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together. Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.
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An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.
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Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.
The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions.
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.
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