Hyaluronic acid Cosmetic Grade

Characteristics

White or almost white, very hygroscopic grain or powder, without odor, turn to clear solution when dissolved in water; insoluble in ethanol,acetone and aether.

pH(0.1% water solution)

6.0-7.5

Molecular weight

Practical value

Loss on drying

≤10.0%

Pesidue on ignition

≤13.0%

Heavy metals(as Pb)

≤20ug/g

Arsenicum

≤2ug/g

Glucuronic acid

≥42.0%

Microbial Examination

Bacteria counts      ≤100CFU/g

Mold&Yeast         ≤100CFU/g

Escherichia coli       negative

Staphylococcus aureus  negative

Characteristics

White or almost white, very hygroscopic grain or powder, without odor, turn to clear solution when dissolved in water; insoluble in ethanol, aceton and aether.

pH(1% water solution)

6.0-7.5

Transparency

≥99.0%

Loss on drying

≤10.0%

Kinematic viscosity

Practical value

Molecular weight

≥1.00×106

Protein

≤0.1%

Heavy metals(as Pb)

≤20ug/g

Glucuronic Acid

≥44.0%

Sodium Hyaluronate

≥91.0%

Microbial Examination

Bacteria counts      ≤10CFU/g

Mold&Yeast         ≤10CFU/g

Escherichia coli       negative

Staphylococcus aureus  negative

Characteristics

White or almost white, very hygroscopic grain or powder, without odor, turn to clear solution when dissolved in water; insoluble in ethanol, aceton and aether.

pH(1% water solution)

6.0~7.5

Molecular weight

(0.8~2.0×106)

Protein

≤0.05%

Loss on drying

≤8.0%

Residue on ignition

＜15%

Heavy metals(as Pb)

＜10ug/g

Arsenic

＜2ug/g

Glucuronic Acid

≥45.0%

Microbial Examination

Bacterial endotoxin      ＜1EU/mg

Sterility                Complies