Medroxyprogesterone 17-acetate Bulk Supply High Purity Pharmaceutical API Medroxyprogesterone Acetate CAS 71-58-9

Superiority:

Product Description

What is Medroxyprogesterone 17-acetate

Medroxyprogesterone 17-acetate (MPA) is a synthetic progestin used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis. It is a more potent progestin that the nonacetylated form.

Medroxyprogesterone acetate (MPA) is used as birth control and as part of menopausal hormone therapy. It is also used to treat endometriosis, abnormal uterine bleeding, abnormal sexuality in males, and certain types of cancer. It is used by mouth or injection into a muscle or under the skin.

Medical abortion brings less pain to patients, and is safe and convenient. However, after medical abortion, the human chorionic gonadotropin in the blood decreases and the estrogen rises slowly, and the shedding of the decidua chorion is slowed down, resulting in excessive vaginal bleeding for a long time, and at the same time affecting the repair of the endometrium. Mifepristone in combination with misoprostol is the most commonly used drug for terminating early pregnancy, but the drug has more bleeding and longer bleeding time after abortion. Therefore, it is necessary to seek conservative treatment methods to reduce vaginal bleeding after medical abortion. Some scholars have used traditional Chinese medicine preparations such as promoting blood circulation to remove blood stasis to stop bleeding and promoting muscle growth in the treatment of vaginal bleeding after medical abortion, but the effect is not exact. At present, continuous therapy of estrogen and progesterone is mostly used in domestic patients with vaginal bleeding after medical abortion for more than 14 days. However, this method has large side effects, complicated administration methods, limited patient compliance, and general clinical feasibility. Medrogesterone is a synthetic luteal progesterone. The raw material is a white or off-white crystalline powder. It is easily soluble in chloroform, soluble in acetone, slightly soluble in ethyl acetate, and slightly soluble in anhydrous ethanol. ,not soluble in water. Moxiprogesterone can repair the endometrium quickly. After the drug is stopped for a period of time, withdrawal bleeding may occur. To the effect of drug-induced curettage, it can replace uterine evacuation, and after adjuvant anti-infective treatment, it can reduce the complications of drug abortion, and at the same time, it can quickly reduce bleeding and stop bleeding as soon as possible. Good clinical feasibility; in addition, it can also be widely used in the treatment of irregular menstruation, dysmenorrhea, etc., injection can be used as a long-acting contraceptive, high-dose for the treatment of breast cancer, etc.; short-course (14d) oral medroxyprogesterone acetate ( 60mg/d) can effectively improve hypoxemia and carbon dioxide retention in male patients with chronic respiratory failure, and it is convenient to take the medicine every day; there is no increase in blood lipids and blood pressure after short-term medication, which has certain clinical value; medroxyprogesterone acetate Ketones can also be used to treat female hirsutism, intramuscular injection, each 100mg, 2 times a month.

For the treatment of advanced breast cancer, endometrial adenocarcinoma and kidney cancer