GMP manufacturer High Purity Benzbromarone Powder CAS 3562-84-3

Superiority:

English name: Benzbromarone

CAS Number: 3562-84-3

Molecular formula: C17H12Br2O3

Molecular weight: 424.08

EINECS Number: 222-630-7

Melting point: 151°

Boiling point: 514.1±50.0°C (Predicted)

Density: 1.6211 (roughestimate)

Refractive index: 1.6010 (estimate)

Storage conditions: Inert at mosphere, 2-8°C

Benzbromarone, also known as benzobromocoumarin or gout (Benzybromaron, Exurate), is a representative derivative of benzofuran. It has a dual effect on reducing the concentration of blood uric acid, relieving pain and swelling, eliminating gout stones, and can be used to treat primary hyperuricemia, intermittent gouty arthritis and gouty nodules.

1. Benzbromarone combined with traditional Chinese medicine in the treatment of gout. The combination of traditional Chinese and Western medicine is used to treat gout and gastrointestinal related diseases. The research shows that it is very feasible. The combination of drugs can not only effectively control the concentration of uric acid, but also quickly relieve symptoms, which is a strong and effective method.

2. The combination of Benzbromarone and Weicao Capsules in the treatment of gout mainly exerts the following effects: promotes uric acid excretion and effectively protects renal function; reduces the concentration of blood uric acid in patients, thereby reducing the deposition in the renal interstitium and reducing proteinuria; Joint inflammation and edema; it can reduce lipid deposition in the kidneys by reducing lipids, which is beneficial to the protection of renal function.

3. Benzbromarone combined with specific electromagnetic waves (TDP) in the treatment of gouty arthritis The thermal effect produced by the specific electromagnetic spectrum emitted by the specific electromagnetic waves (TDP) can effectively improve the blood circulation and PH value of the diseased joints, thereby inhibiting The formation of urate crystals plays an anti-inflammatory and analgesic effect; when a specific electromagnetic wave (TDP) is used in combination with a large dose of benzbromarone, it can more effectively organize the reabsorption of uric acid by the renal tubules and reduce the blood uric acid level.

4. The combination of benzbromarone and allopurinol (allopurinol) in the stable phase of gout, because benzbromarone can have a strong reversible inhibitory effect on the urate-anion exchange system in the renal tubule, reduce renal The reabsorption of uric acid by tubules, and allopurinol can effectively inhibit the last step in the synthesis of uric acid, thereby reducing the level of blood uric acid. , especially for patients with hyperuricemia and a large number of tophi deposits, the combined use of the two drugs can more effectively exert the effect of reducing uric acid.

5. Benzbromarone combined with indapamide (Indapamide) for the treatment of blood pressure and uric acid Indapamide is a long-acting and powerful antihypertensive drug, belonging to the sulfonamide diuretics, its mechanism of treatment of hypertension It is diuretic and calcium antagonistic. Indapamide can also treat hypertensive patients, and better therapeutic effect can be obtained by combined use of benzbromarone. This method has been verified and is worthy of clinical application.

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