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English name: Tazobactam acid
CAS number: 89786-04-9
Molecular formula: C10H12N4O5S
Molecular weight: 300.29
EINECS Number: 618-303-7
Melting point: 115-145℃
Boiling point: 77℃
Density: 1.92±0.1g/cm3(Predicted)
RTECS No.: XI0191400
Flash Point: >110°(230°F)
Storage conditions: Sealed in dry, Store in freezer, under-20°C
This product, also known as tazobactam, is a derivative of sulbactam. It is an irreversible competitive β-lactamase inhibitor. Both β-lactamase and chromosome-mediated β-lactamase produced by Proteus, Bacteroides, Klebsiella and other bacteria have strong inhibitory effects. The inhibitory effect is better than that of clavulanic acid and sulbactam, and also has inhibitory effect on some chromosome-mediated type I enzymes. It has little effect on Pseudomonas aeruginosa and other Pseudomonas and Serratia. Only weak antibacterial activity.
Tazobactam Sodium: C10H11N4NaO5S. [89785-84-2]. Amorphous solid, melting point >170°C (decomposition).
1. Penicillane sulfone β-lactamase inhibitors are effective for all types I to VI 3-lactamases, especially for type I enzymes. It has low toxicity, good stability and strong inhibitory activity. It is clinically used to treat infections caused by a variety of bacteria, including aerobic and anaerobic bacteria, including lower respiratory tract infections, skin and abdominal infections.
2. β-lactamase inhibitor, the third-generation antibacterial strong synergist, combined with piperacillin or cefoperazone can enhance the efficacy and prolong the action time of both. When used in combination with piperacillin sodium, tazobactam sodium has obvious synergistic effect and is widely used in the treatment of severe systemic and local infections, abdominal infections, lower respiratory tract infections, soft tissue infections, sepsis, etc. The compound agent has a wider antibacterial spectrum and indications, showing great advantages in overcoming drug resistance.
3. It is a β-lactamase inhibitor and a third-generation antibacterial strong synergist. Combination with piperacillin or cefoperazone can enhance the efficacy and prolong the action time of the two.
Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together. Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.
Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.
An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.
1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.
2.We can provide you with ten thousands of products of different levels.
3. We offer convenient one-station purchasing service.
(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.
Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.
The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions.
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.
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