Pharmaceutical Grade Glaucoma Eye Drops Ophthalmic Solution Brinzolomide CAS: 138890-62-7

Pharmaceutical Grade Glaucoma Eye Drops Ophthalmic Solution Brinzolomide CAS: 138890-62-7

Min.Order / FOB Price:Get Latest Price

1 Gram	FOB Price:USD 0.0200 -0.0300

1 Gram

FOB Price:USD 0.0200 -0.0300

Min.Order :1 Gram
Purity: 99%+
Payment Terms : L/C,D/A,D/P,T/T,Other

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Quick Details

Appearance:White powder
Application:1. Carbonic anhydrase inhibitor, suitable for high intraocular pressure caused by open-angle glaucoma or other reasons. 2. Heterocyclic sulfonamide carbonic anhydrase inhibitors
PackAge:bag or barrel or drum
ProductionCapacity:6000|Metric Ton|Day
Storage:Store at room temperature
Transportation:by express or air or sea

Superiority:

Product Name: Brinzolomide
CAS No.: 138890-62-7
Molecular Formula: C12H21N3O5S3
Molecular Weight: 383.51g/mol
Purity : 99% USP35
Appearance: white crystalline powder
Typical use:Glaucoma Eye Drops
Shelf Life :2 years
Storage:Room temperature away from light
Brinzolamide is a new type of topical heterocyclic sulfonamide carbonic anhydrase inhibitor, which has strong affinity and inhibitory effect on carbonic anhydrase isozyme II (CAII) in human ciliary body, with selectivity and high affinity And obviously inhibit the activity of carbonic anhydrase isoenzyme II, effectively reduce intraocular pressure, has the advantages of high efficiency, low toxicity, and small side effects, its physiological pH value and suspension design make the drug eye comfortable. favored by patients. It can be used as a single treatment drug for patients with ineffective or contraindicated beta-blockers, or as a synergistic therapy with beta-blockers. Longer half-life in the body, choroid, retina, lens and blood. The use of Pelimin for rabbit eye drops can also increase the blood flow of the optic disc, which is beneficial to glaucoma patients with optic neuropathy, and has become the first-line drug for the treatment of open-angle glaucoma. Carbonic anhydrase (CA) is one of the main protein components of erythrocytes, and is second only to hemoglobin in erythrocytes, and is present in many body tissues including eye tissue. Carbonic anhydrase catalyzes the hydration of carbon dioxide to carbonic acid, and the reversible reaction of carbonic acid dehydration. Inhibition of carbonic anhydrase in the ciliary body of the eye can reduce the secretion of aqueous humor. Possibly by reducing the production of bicarbonate ions, the transport of sodium and water is reduced, which ultimately reduces intraocular pressure. Intraocular pressure is an important risk factor for glaucomatous optic nerve damage and glaucomatous visual field defect. Brinzolamide mainly inhibits the predominant carbonic anhydrase type 2 isoenzyme in the eye tissue. In vitro, the 50% effective inhibitory concentration is 3.2nM, and the Ki value for carbonic anhydrase type 2 isoenzyme is 0.13nM .

1. Carbonic anhydrase inhibitor, suitable for high intraocular pressure caused by open-angle glaucoma or other reasons.

2. Heterocyclic sulfonamide carbonic anhydrase inhibitors

Details:

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together. Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.

1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions.
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.

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