Super Low Price Supply Nutrition Powder L-Alanyl-L-Glutamine CAS 39537-23-0 with Fast Safe Delivery DDP Free Customs

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English name: L-Alanyl-L-Glutamine

CAS number: 39537-23-0

Molecular formula: C8H15N3O4

Molecular weight: 217.22

EINECS Number: 475-290-9

Melting point: 215°C

Boiling point: 615℃

Density: 1.305±0.06g/cm3(Predicted)L-Glutamine (Gln) is an essential precursor for the biosynthesis of nucleic acid. It is a very abundant amino acid in the body, accounting for about 60% of the free amino acids in the body. It is a regulator of protein synthesis and decomposition. It is an important matrix excreted by the carrier kidneys from peripheral tissues to internal organs, and plays an important role in the body's immune function and wound repair. However, due to the low solubility of L-glutamine, it is unstable in aqueous solutions and cannot tolerate heat sterilization. Heating is prone to produce toxic substances, which limits its application in parenteral nutrition. In clinical practice, L-alanyl-L-glutamine (Ala-Gln) dipeptide is commonly used as the application carrier of Gln. L-alanyl-L-glutamine has stable properties and is easily soluble and can withstand high temperature disinfection. It can be rapidly hydrolyzed into L-glutamine to play its role in the body. It has high bioavailability and a wide range of applications, making up for L-glutamine. The deficiency of aminoamide plays an important role especially in patients with sudden trauma. In extraordinary times, L-alanyl-L-glutamic acid amide plays an important role in safeguarding the health of soldiers and improving the combat effectiveness of the army, and its application in parenteral nutrition has been paid more and more attention. At present, the vast majority of domestic L-alanyl-L-glutamic acid amides rely on imports, and will face a situation where there is no medicine to buy in extraordinary times, and its market prospects are limitless. L-Alanyl-L-Glutamine, referred to as Ala-Gln for short, its 20% intravenous injection was developed and produced by Fresenius AG, Germany. It was registered and listed in Germany in April 1995, and its trade name is Dipeptamin was registered and listed in China in 1999 under the trade name of 20% Dipeptamin (power peptide). C-glutamine dipeptide is clinically used as a donor of glutamine for parenteral nutrition. Like normal saline and glucose, it is a necessity for rescuing patients, and its market prospects are unlimited. L-alanyl-L-glutamyl is a chemically synthesized dipeptide, which is degraded into L-glutamine and alanine for nutritional drugs in the body, and supplies the body for material synthesis or energy consumption. This drug is used for severe catabolic diseases. , such as burn trauma, major surgery, acute and chronic infections, bone marrow transplantation and multiple organ dysfunction syndrome, intestinal insufficiency such as short bowel syndrome and mucosal damage caused by radiotherapy and chemotherapy, immunodeficiency syndrome such as AIDS, critical illness or bone marrow transplantation It has a good therapeutic effect on diseases such as immunodeficiency and other diseases complicated by it, and it is widely used in clinical practice.

1. This product is a component of parenteral nutrition and is suitable for patients who need to supplement glutamine, including patients in catabolic and hypermetabolic conditions. Such as: trauma, burns, large and medium-sized surgery, bone marrow and other organ transplantation, gastrointestinal syndrome, tumor, severe infection and other ICU patients in a state of stress. This product is a supplement to amino acid solution and should be added to other amino acid solutions or infusions containing amino acids when used.

2. A dipeptide used as a glutamine substitute in mammalian cell culture medium; glutamine is unstable in solution, and the formed ammonia has deleterious effects in cell culture; Ala-Glu is stable to heat sterilization The effect of forming ammonia is less than that of glutamine. As one of the medium components, it is beneficial to exert its advantages

3. It can be used as a substitute for glutamate in mammalian cell culture medium, and it is stable during heat sterilization.