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Amadis Chemical offer CAS#34973-08-5;CAT#A822487 Gonadorelin acetate CAS 34973-08-5
English name: Gonadorelin acetate
CAS number: 34973-08-5
Molecular formula: C57H79N17O15
Molecular weight: 1242.36
EINECS Number: 683-628-3
Melting point:>155oC(dec.)
Storage conditions:Hygroscopic,Refrigerator,Under inert atmosphere
Solubility: Methanol(Slightly), Water(Slightly)
Form:Solid Color: White to Off-White
Stability:Hygroscopic
Gonadorelin acetate is secreted by the pituitary in vivo and can stimulate the anterior pituitary to secrete gonadotropins FSH and LH. LH can promote the synthesis and secretion of androgens in the interstitium of the male testis. The dual effects of LH and FSH can promote ovarian synthesis and secretion of estrogen. Continuous application of this product has a biphasic effect on the pituitary: at the beginning, it can promote the secretion of LH and FSH from the anterior pituitary, and increase the LH, FSH and sex hormones in the plasma; after a long time, it can lead to the decrease of LHRH receptors in the pituitary and prevent the secretion of LH in the pituitary. , thereby blocking the synthesis and secretion of testosterone, achieving the same effect as orchiectomy. In women, it blocks the synthesis and secretion of estrogen to achieve the same effect as oophorectomy. Therefore, it can treat hormone-dependent prostate cancer and breast cancer, as well as endometriosis. This strain is a synthetic product. It is mainly used as an ovulation-stimulating drug in the treatment of infertility and primary ovarian insufficiency caused by hypothalamic amenorrhea, especially for those who are ineffective against clomiphene; Many, pituitary tumors. Intravenous injection 3min to peak. t1/2 is about 6min, and it is rapidly metabolized by the kidney and excreted.
Multiple pregnancies, inflammation at the injection site, and occasional temporary penile enlargement have been reported during the use of gonarelin acetate. Those who are allergic to benzyl alcohol should not use it. Injections should be stored at 2-8°C in the dark; powder injections should be stored at 8-20°C.
Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together. Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.
Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.
An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.
1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.
2.We can provide you with ten thousands of products of different levels.
3. We offer convenient one-station purchasing service.
(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.
Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.
The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions.
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.
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