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CAS 319-78-8 D-Isoleucine (2R,3R)-2-Amino-3-methylpentanoic acid
English name: (2R,3R)-2-Amino-3-methylpentanoic acid
CAS Number: 319-78-8
Molecular formula: C6H13NO2
Molecular weight: 131.17
EINECS Number: 206-269-2
Melting point: 272-274°C
Specific rotation: -37º(c=5,1NHCl24ºC)
Boiling point: 225.8±23.0°C (Predicted)
Density: 1.1720(estimate)
Refractive index: -40.5°(C=4,6mol/LHCl)
Storage conditions: Sealed in dry, RoomTemperature
Solubility: AqueousAcid(Slightly), Water(Slightly)
Acidity coefficient: (pKa) 2.57±0.24 (Predicted)
Form: Solid
Color: White to Off-White
D-Isoleucine is an important source of organic chirality, which is widely used in the field of medicine. As an optically active organic acid, it has an irreplaceable role in the asymmetric synthesis of some chiral compounds. It is mainly used in the preparation of chiral drugs, chiral additives, chiral auxiliaries, etc. At the same time, it is also an important intermediate for the synthesis of antibacterial, anti-tumor, new broad-spectrum antibiotics, and pharmaceutical supplements.
White flake crystal or crystalline powder, odorless, slightly bitter in taste; soluble in water, slightly soluble in ethanol, insoluble in ether; decomposition point is 283-284°C; specific rotation [α]20D-12.4° (0.5- 2.0 mg/ml, H2O), [α]25D-30.5° (0.5-2.0 mg/ml, 5mol/L HCl).
For biochemical research, it is used for nutritional supplements in medicine. D-Isoleucine ((R)-Isoleucine), a stereoisomer of isoleucine, is a selective activator of the Asc-1 antiporter and enhances hippocampal CA1-CA3 by releasing endogenous D-serine long-term synergistic effect
Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together. Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.
Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.
An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.
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Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.
The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions.
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.
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